MANAGEMENT OF RETURN TO PHYSICAL ACTIVITY AFTER CONCUSSION: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.31435/ijitss.4(48).2025.4496Keywords:
Sport-Related Concussion, Return to Activity, Aerobic Exercise, Active Rehabilitation, Progressive Exercise ProtocolAbstract
Sport-related concussion management has undergone significant evolution, shifting from prolonged rest to active rehabilitation approaches. This systematic review examines current evidence regarding optimal return to physical activity protocols following sport-related concussion. A comprehensive literature search was conducted using PubMed, CINAHL, SPORTDiscus, and Web of Science databases, focusing on studies published between 2018-2023. Inclusion criteria comprised randomized controlled trials, systematic reviews, and prospective cohort studies examining physical activity interventions during concussion recovery. Contemporary evidence strongly supports brief initial rest (24-48 hours) followed by progressive, sub-threshold aerobic exercise. Multiple randomized controlled trials demonstrate that early controlled exercise accelerates recovery without adverse effects, reducing median recovery time from 17 to 13 days. The Buffalo Concussion Treadmill Test enables individualized exercise prescription at 80-90% of symptom-threshold heart rate. Multimodal approaches targeting specific symptom clusters (vestibular, cervicogenic, autonomic) show superior outcomes compared to generic protocols. Implementation remains inconsistent, with only 45% of practitioners regularly prescribing structured exercise despite strong evidence. Active rehabilitation through controlled, progressive exercise represents the current evidence-based standard for concussion management. Early sub-threshold aerobic exercise, initiated within one week of injury, optimizes recovery while minimizing persistent symptoms. Future research should focus on precision medicine approaches and optimal protocols for special populations.
References
Pierpoint, L. A., & Collins, C. (2021). Epidemiology of sport-related concussion. Clinical Sports Medicine, 40(1), 1-10. https://doi.org/10.1016/j.csm.2020.08.013
Gornall, A., Takagi, M., Morawakage, T., Liu, X., & Anderson, V. (2021). Mental health after paediatric concussion: A systematic review and meta-analysis. British Journal of Sports Medicine, 55(18), 1048-1058. https://doi.org/10.1136/bjsports-2020-103548
Churchill, N. W., Hutchison, M. G., Graham, S. J., & Schweizer, T. A. (2018). Connectomic markers of symptom severity in sport-related concussion: Whole-brain analysis of resting-state fMRI. NeuroImage: Clinical, 18, 518-526. https://doi.org/10.1016/j.nicl.2018.02.011
Silverberg, N. D., Iaccarino, M. A., Panenka, W. J., Iverson, G. L., McCulloch, K. L., Dams-O'Connor, K., Reed, N., & McCrea, M. (2020). Management of concussion and mild traumatic brain injury: A synthesis of practice guidelines. Archives of Physical Medicine and Rehabilitation, 101(2), 382-393. https://doi.org/10.1016/j.apmr.2019.10.179
McCrory, P., Meeuwisse, W., Dvořák, J., Aubry, M., Bailes, J., Broglio, S., Cantu, R. C., Cassidy, D., Echemendia, R. J., Castellani, R. J., Davis, G. A., Ellenbogen, R., Emery, C., Engebretsen, L., Feddermann-Demont, N., Giza, C. C., Guskiewicz, K. M., Herring, S., Iverson, G. L., ... & Vos, P. E. (2017). Consensus statement on concussion in sport—The 5th International Conference on Concussion in Sport held in Berlin, October 2016. British Journal of Sports Medicine, 51(11), 838-847. https://doi.org/10.1136/bjsports-2017-097699
Leddy, J. J., Haider, M. N., Ellis, M. J., Mannix, R., Darling, S. R., Freitas, M. S., Suffoletto, H. N., Leiter, J., Cordingley, D. M., & Willer, B. (2019). Early subthreshold aerobic exercise for sport-related concussion: A randomized clinical trial. JAMA Pediatrics, 173(4), 319-325. https://doi.org/10.1001/jamapediatrics.2018.4397
Carter, K. M., Pauhl, A. N., & Christie, A. D. (2021). The role of active rehabilitation in concussion management: A systematic review and meta-analysis. Medicine & Science in Sports & Exercise, 53(9), 1835-1845. https://doi.org/10.1249/MSS.0000000000002663
Petit, K. M., & Covassin, T. (2021). College athletic trainers' perceptions of rest and physical activity when managing athletes with a sport-related concussion. Journal of Sport Rehabilitation, 56(2), 196-202. https://doi.org/10.1123/jsr.2019-0084
Iverson, G. L., Gardner, A. J., Terry, D. P., Ponsford, J. L., Sills, A. K., Broshek, D. K., & Solomon, G. S. (2017). Predictors of clinical recovery from concussion: A systematic review.
British Journal of Sports Medicine, 51(12), 941-948. https://doi.org/10.1136/bjsports-2017-097729
Giza, C. C., & Hovda, D. A. (2014). The new neurometabolic cascade of concussion. Neurosurgery, 75(Suppl. 4), S24-S33. https://doi.org/10.1227/NEU.0000000000000505
Wu, Y. C., Harezlak, J., Elsaid, N. M. H., Lin, Z., Wen, Q., Mustafi, S. M., Riggen, L. D., Koch, K. M., Nencka, A. S., Meier, T. B., Mayer, A. R., Wang, Y., Guskiewicz, K. M., Mihalik, J. P., LaConte, S. M., Duma, S. M., Broglio, S. P., Saykin, A. J., McCrea, M. A., & McAllister, T. W. (2020). Longitudinal white-matter abnormalities in sports-related concussion: A diffusion MRI study. Neurology, 95(7), e781-e792. https://doi.org/10.1212/WNL.0000000000009930
Mutch, W. A. C., Ellis, M. J., Ryner, L. N., McDonald, P. J., Morissette, M. P., Pries, P., Essig, M., Mikulis, D. J., Duffin, J., & Fisher, J. A. (2018). Patient-specific alterations in CO2 cerebrovascular responsiveness in acute and sub-acute sports-related concussion. Frontiers in Neurology, 9, Article 23. https://doi.org/10.3389/fneur.2018.00023
Purkayastha, S., Stokes, M., & Bell, K. R. (2019). Autonomic nervous system dysfunction in mild traumatic brain injury: A review of related pathophysiology and symptoms. Brain Injury, 33(9), 1129-1136. https://doi.org/10.1080/02699052.2019.1631488
Di Battista, A. P., Churchill, N., Rhind, S. G., Richards, D., & Hutchison, M. G. (2020). The relationship between symptom burden and systemic inflammation differs between male and female athletes following concussion. BMC Immunology, 21(1), Article 11. https://doi.org/10.1186/s12865-020-0339-3
Ellis, M. J., Leddy, J., Cordingley, D., & Willer, B. (2018). A physiological approach to assessment and rehabilitation of acute concussion in collegiate and professional athletes. Frontiers in Neurology, 9, Article 1115. https://doi.org/10.3389/fneur.2018.01115
Thomas, D. G., Apps, J. N., Hoffmann, R. G., McCrea, M., & Hammeke, T. (2015). Benefits of strict rest after acute concussion: A randomized controlled trial. Pediatrics, 135(2), 213-223. https://doi.org/10.1542/peds.2014-0966
Ettenhofer, M. L., Remigio-Baker, R. A., Bailie, J. M., Cole, W. R., & Gregory, E. (2020). Best practices for progressive return to activity after concussion: Lessons learned from a prospective study of U.S. military service members. Neurotrauma Reports, 1(1), 137-145. https://doi.org/10.1089/neur.2020.0023
Schneider, K. J., Leddy, J. J., Guskiewicz, K. M., Seifert, T., McCrea, M., Silverberg, N. D., Feddermann-Demont, N., Iverson, G. L., Hayden, A., & Makdissi, M. (2017). Rest and treatment/rehabilitation following sport-related concussion: A systematic review. British Journal of Sports Medicine, 51(12), 930-934. https://doi.org/10.1136/bjsports-2016-097475
Haider, M. N., Leddy, J. J., Wilber, C. G., Viera, K. B., Bezherano, I., Wilkins, K. J., Miecznikowski, J. C., & Willer, B. S. (2019). The predictive capacity of the Buffalo Concussion Treadmill Test after sport-related concussion in adolescents. Frontiers in Neurology, 10, Article 395. https://doi.org/10.3389/fneur.2019.00395
Buckley, T. A., Munkasy, B. A., Evans, K. M., & Clouse, B. (2022). Acute physical and mental activity influence on concussion recovery. Medicine & Science in Sports & Exercise, 54(2), 307-312. https://doi.org/10.1249/MSS.0000000000002787
DeMatteo, C., Randall, S., Lin, C. Y., & Claridge, E. A. (2019). What comes first: Return to school or return to activity for youth after concussion? Maybe we don't have to choose. Frontiers in Neurology, 10, Article 792. https://doi.org/10.3389/fneur.2019.00792
Wiebe, D. J., Bretzin, A. C., & D'Alonzo, B. A. (2022). Progression through return-to-sport and return-to-academics guidelines for concussion management and recovery in collegiate student athletes: Findings from the Ivy League-Big Ten Epidemiology of Concussion Study. British Journal of Sports Medicine, 56(14), 801-811. https://doi.org/10.1136/bjsports-2021-104451
Silverberg, N. D., & Otamendi, T. (2019). Advice to rest for more than 2 days after mild traumatic brain injury is associated with delayed return to productivity: A case-control study. Frontiers in Neurology, 10, Article 362. https://doi.org/10.3389/fneur.2019.00362
Lishchynsky, J. T., Rutschmann, T. D., Toomey, C. M., Palacios-Derflingher, L., Emery, C. A., & Schneider, K. J. (2019). The association between moderate-to-vigorous physical activity and recovery following sport-related concussion in youth ice hockey players. Frontiers in Neurology, 10, Article 588. https://doi.org/10.3389/fneur.2019.00588
Collins, M. W., Kontos, A. P., Okonkwo, D. O., Almquist, J., Bailes, J., Barisa, M., Bazarian, J., Bloom, O. J., Brody, D. L., Cantu, R., Cardenas, J., Clugston, J., Cohen, R., Echemendia, R., Elbin, R. J., Ellenbogen, R., Fonseca, J., Gioia, G., Guskiewicz, K., ... & Zafonte, R. (2016). Statements of agreement from the Targeted Evaluation and Active Management (TEAM) approaches to treating concussion meeting held in Pittsburgh, October 15-16, 2015. Neurosurgery, 79(6), 912-929. https://doi.org/10.1227/NEU.0000000000001447
Lawrence, D. W., Richards, D., Comper, P., & Hutchison, M. G. (2018). Earlier time to aerobic exercise is associated with faster recovery following acute sport concussion. PLoS One, 13(4), Article e0196062. https://doi.org/10.1371/journal.pone.0196062
Broglio, S. P., Harezlak, J., Katz, B., Zhao, S., McAllister, T., & McCrea, M. (2019). Acute sport concussion assessment optimization: A prospective assessment from the CARE Consortium. Sports Medicine, 49(12), 1977-1987. https://doi.org/10.1007/s40279-019-01155-0
Shahim, P., Politis, A., van der Merwe, A., Moore, B., Chou, Y. Y., Pham, D. L., Butman, J. A., Diaz-Arrastia, R., Gill, J. M., Brody, D. L., Zetterberg, H., Blennow, K., & Chan, L. (2020). Neurofilament light as a biomarker in traumatic brain injury. Neurology, 95(6), e610-e622. https://doi.org/10.1212/WNL.0000000000009983
Murray, D. A., Meldrum, D., & Lennon, O. (2017). Can vestibular rehabilitation exercises help patients with concussion? A systematic review of efficacy, prescription and progression patterns. British Journal of Sports Medicine, 51(5), 442-451. https://doi.org/10.1136/bjsports-2016-096081
Kennedy, E., Quinn, Z., Tumilty, S., & Chapple, C. M. (2017). Clinical characteristics and outcomes of treatment of the cervical spine in patients with persistent post-concussion symptoms: A retrospective analysis. Musculoskeletal Science & Practice, 29, 91-98. https://doi.org/10.1016/j.msksp.2017.03.002
Wickwire, E. M., Williams, S. G., Roth, T., Capaldi, V. F., Jaffe, M., Moline, M., Motamedi, G. K., Morgan, G. W., Mysliwiec, V., Germain, A., Pazdan, R. M., Ferziger, R., Balkin, T. J., MacDonald, M. E., Macek, T. A., Yochelson, M. R., Scharf, S. M., & Lettieri, C. J. (2016). Sleep, sleep disorders, and mild traumatic brain injury: What we know and what we need to know: Findings from a National Working Group. Neurotherapeutics, 13(2), 403-417. https://doi.org/10.1007/s13311-016-0429-3
Watanabe, T. K., Bell, K. R., Walker, W. C., & Schomer, K. (2012). Systematic review of interventions for post-traumatic headache. PM&R, 4(2), 129-140. https://doi.org/10.1016/j.pmrj.2011.06.003
Oliver, J. M., Anzalone, A. J., & Turner, S. M. (2018). Protection before impact: The potential neuroprotective role of nutritional supplementation in sports-related head trauma. Sports Medicine, 48(Suppl. 1), 39-52. https://doi.org/10.1007/s40279-017-0847-3
McCrea, M., Broglio, S. P., McAllister, T. W., Gill, J., Giza, C. C., Huber, D. L., Harezlak, J., Cameron, K. L., Houston, M. N., McGinty, G., Jackson, J. C., Guskiewicz, K., Mihalik, J., Brooks, M. A., Duma, S., Rowson, S., Nelson, L. D., Pasquina, P., Meier, T. B., & CARE Consortium Investigators. (2020). Association of blood biomarkers with acute sport-related concussion in collegiate athletes: Findings from the NCAA and Department of Defense CARE Consortium. JAMA Network Open, 3(1), Article e1919771. https://doi.org/10.1001/jamanetworkopen.2019.19771
Kontos, A. P., Eagle, S. R., Marchetti, G., Sinnott, A., Mucha, A., Port, N., Radomski, C., Schatz, P., Elbin, R. J., Collins, M. W., Holland, C. L., & CARE Consortium Investigators. (2021). Discriminative validity of Vestibular Ocular Motor Screening in identifying concussion among collegiate athletes: A National Collegiate Athletic Association-Department of Defense Concussion Assessment, Research, and Education Consortium study. American Journal of Sports Medicine, 49(8), 2211-2217. https://doi.org/10.1177/03635465211012359
Patricios, J. S., Schneider, G. M., van Ierssel, J., Purcell, L. K., Davis, G. A., Echemendia, R. J., Fremont, P., Fuller, G. W., Herring, S. A., Kutcher, J. S., Leddy, J. J., Makdissi, M., Master, C. L., McNamee, M., Meeuwisse, W. H., Putukian, M., Sills, A. K., Turner, M., Vaandering, K., ... & Zemek, R. L. (2023). Beyond acute concussion assessment to office management: A systematic review informing the development of a Sport Concussion Office Assessment Tool (SCOAT6) for adults and children. British Journal of Sports Medicine, 57(11), 737-748. https://doi.org/10.1136/bjsports-2023-106897
Yeates, K. O., Ris, M. D., Taylor, H. G., Bigler, E. D., Cohen, M. L., Craig, W., Esopenko, C., Gerry Taylor, H., Minich, N., Rubin, K., Vannatta, K., Gerhardt, C. A., Stancin, T., & Walz, N. C. (2017). Advancing Concussion Assessment in Pediatrics (A-CAP): A prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: study protocol. BMJ Open, 7(7), Article e015290. https://doi.org/10.1136/bmjopen-2017-017012
Nagar, A., Bergmann, C., Schultz, V., Wellwood, K., Barnes-Wood, E., & Al-Khazraji, B. K. (2022). Applications of machine learning to the identification of anomalous ER claims (arXiv:2206.08093). arXiv. https://doi.org/10.48550/arXiv.2206.08093
Master, C. L., Katz, B. P., Arbogast, K. B., McCrea, M. A., McAllister, T. W., Pasquina, P. F., Lapradd, M., Zhou, W., Winston, F. K., Grady, M. F., & CARE Consortium Investigators. (2021). Differences in sport-related concussion for female and male athletes in comparable sports: A study from the NCAA-DoD Concussion Assessment, Research and Education (CARE) Consortium. British Journal of Sports Medicine, 55(24), 1387-1394. https://doi.org/10.1136/bjsports-2020-103316
Rice, S. M., Parker, A. G., Rosenbaum, S., Bailey, A., Mawren, D., & Purcell, R. (2018). Sport-related concussion and mental health outcomes in elite athletes: A systematic review. Sports Medicine, 48(2), 447-465. https://doi.org/10.1007/s40279-017-0810-3
Churchill, N. W., Hutchison, M. G., Graham, S. J., & Schweizer, T. A. (2019). Mapping brain recovery after concussion: From acute injury to 1 year after medical clearance.
Neurology, 93(21), e1980-e1992. https://doi.org/10.1212/WNL.0000000000008523
Downloads
Published
Issue
Section
License
All articles are published in open-access and licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). Hence, authors retain copyright to the content of the articles.
CC BY 4.0 License allows content to be copied, adapted, displayed, distributed, re-published or otherwise re-used for any purpose including for adaptation and commercial use provided the content is attributed.

