PERIOPERATIVE ANESTHETIC MANAGEMENT IN PATIENTS WITH HEART FAILURE: FROM RISK ASSESSMENT TO HEMODYNAMIC OPTIMIZATION, INTEGRATING FUNCTIONAL CAPACITY ASSESSMENT AND EXERCISE PREHABILITATION – A NARRATIVE REVIEW
DOI:
https://doi.org/10.31435/ijitss.2(50).2026.5366Keywords:
HF, HFrEF, HFpEF, Perioperative Care, Hemodynamic Monitoring, Quality of CareAbstract
Background: Heart failure (HF) increases perioperative complications and mortality in patients undergoing non-cardiac surgery. Both heart failure with reduced ejection fraction and preserved ejection fraction increase cardiovascular risk and require perioperative management.
Aim: This review summarizes evidence on perioperative anesthetic management in patients with HF undergoing non-cardiac surgery, focusing on risk assessment, medical therapy optimization, intraoperative hemodynamic management, fluid therapy, postoperative monitoring and impact of exercise on recovery.
Materials and Methods: This narrative review included PubMed-indexed studies published between 2021 and 2026. ESC consensus statements, randomized trials, and large cohort studies were analyzed to summarize practical recommendations for perioperative management of HF.
Results: Preoperative evaluation should include clinical assessment, natriuretic peptide measurement, and echocardiography. Optimization of medical therapy and euvolemia is essential. During surgery, maintaining MAP ≥ 65 mmHg, careful fluid therapy, and early vasopressor use may reduce myocardial injury.
Conclusions: Perioperative management of patients with heart failure should include risk assessment, prehabilitation, hemodynamic control, multidisciplinary care, and functional capacity evaluation to improve short-term outcomes.
References
Shah, A., Sabharwal, N., & Day, J. R. (2024). Heart failure with preserved ejection fraction: Implications for anaesthesia. BJA Education, 24(5), 155–163. https://doi.org/10.1016/j.bjae.2024.02.003
Gualandro, D. M., Masip, J., Halvorsen, S., Price, S., Rosselló, X., Chioncel, O., Peacock, W. F., Miró, Ò., Oliveira Junior, M. T., Mebazaa, A., Platz, E., Amir, O., Schaubroeck, H., Grand, J., Sionis, A., Tavazzi, G., Pöss, J., Verbrugge, F. H., Gambaro, A., … Mueller, C. (2025). Acute heart failure in non-cardiac surgery. European Heart Journal, 46(40), 4042–4059. https://doi.org/10.1093/eurheartj/ehaf559
Scott, M. J. (2023). Perioperative patients with hemodynamic instability: Consensus recommendations of the Anesthesia Patient Safety Foundation. Anesthesia & Analgesia, 138(4), 713–724. https://doi.org/10.1213/ane.0000000000006789
Schmidt, G., Frieling, N., Schneck, E., Habicher, M., Koch, C., Aßmus, B., & Sander, M. (2024). Comparison of preoperative NT-proBNP and simple cardiac risk scores for predicting postoperative morbidity after non-cardiac surgery with intermediate or high surgical risk. Perioperative Medicine, 13(1). https://doi.org/10.1186/s13741-024-00400-z
Okolo, D., Ugorji, W. S., Gopep, N. S., Oragui, C. C., Ubajaka, C. C., & Okobi, O. E. (2025). Perioperative management of anesthesia in patients with cardiovascular disease: A review of current guidelines in the United States. Cureus. https://doi.org/10.7759/cureus.79355
Schmidt, G. F., Habicher, M., Herrmann, E. J., Kenz, M., Reichert, M., Koch, C., Markmann, M., Schneck, E., Aßmus, B., Sander, M., Frey, U., Güder, G., Meybohm, P., Reuter, D., Saugel, B., Treskatsch, S., Heuschmann, P. U., Nuernberger, C., … Zitzmann, A. (2025). Perioperative interdisciplinary optimisation of patients with heart failure undergoing non-cardiac surgery with intermediate or high surgical risk: The rationale and study protocol for the multicentre, randomised interventional PeriOP-CARE HF trial. Clinical Research in Cardiology, 114(5), 523–531. https://doi.org/10.1007/s00392-025-02626-3
Monaco, F., Bonaccorso, A., D’Andria Ursoleo, J., Pruna, A., Lerose, C. C., Di Prima, A. L., Barucco, G., Landoni, G., & Licheri, M. (2025). Intraoperative global longitudinal strain and strain rate as predictors of unfavorable outcome following on-pump mitral surgery: A prospective observational study. Journal of Anesthesia, Analgesia and Critical Care, 5(1). https://doi.org/10.1186/s44158-025-00288-1
Farooq, Z., Malik, S., Bhat, M., & Farooq, S. (2025). Perioperative cardiac complications and evidence-based strategies for their management. Cureus. https://doi.org/10.7759/cureus.95276
Kirkopoulos, A., M’Pembele, R., Roth, S., Stroda, A., Larmann, J., Gillmann, H., Kotfis, K., Ganter, M. T., Bolliger, D., Filipovic, M., Guzzetti, L., Mauermann, E., Ionescu, D., Spadaro, S., Szczeklik, W., De Hert, S., Beck‐Schimmer, B., Howell, S. J., & Lurati Buse, G. A. (2025). Outcomes in patients with chronic heart failure undergoing non-cardiac surgery: A secondary analysis of the METREPAIR international cohort study. Anaesthesia, 80(8), 861–870. https://doi.org/10.1111/anae.16607
Murthy, N. M., Yoo, T. T., Sanchez, A., Chhitu, M., Abramov, D., Gatling, J., Mamas, M. A., & Parwani, P. (2025). Preoperative diagnostic assessment of patients with cardiovascular risk factors undergoing noncardiac surgery: A 2025 update. Methodist DeBakey Cardiovascular Journal, 21(4), 87–100. https://doi.org/10.14797/mdcvj.1629
Saetang, M., Kunapaisal, T., Limvatanalert, S., Sukitpaneenit, K., Saelim, K., Yongsata, D., Muangsong, O., Bunkerd, M., & Kampeng, S. (2026). Key predictors of 30-day mortality in non-cardiac surgery: Development, key risk factors, and calibration of a risk model. Frontiers in Medicine, 13. https://doi.org/10.3389/fmed.2026.1749782
Li, Q., Liu, Z., He, K., Zhuang, Y., Zhang, J., Wei, B., Che, H., Zhang, B., Jiu, L., Li, J., Song, X., & Dong, W. (2025). Development and validation of an interpretable machine learning model for predicting the risk of non-cardiac surgery postoperative heart failure: A multicenter study. Frontiers in Medicine, 12. https://doi.org/10.3389/fmed.2025.1666885
Arias, H. C. (2025). Anesthesia and intraoperative echocardiography for end-stage heart failure surgery. Annals of Cardiac Anaesthesia, 28(4), 379–391. https://doi.org/10.4103/aca.aca_45_25
Deniau, B., Léopold, V., & Mebazaa, A. (2025). Accurate diagnosis of heart failure and improved perioperative outcomes. British Journal of Anaesthesia, 134(1), 1–4. https://doi.org/10.1016/j.bja.2024.10.003
Skouri, H., Girerd, N., Monzo, L., Petrie, M. C., Böhm, M., Adamo, M., Mullens, W., Savarese, G., Yilmaz, M. B., Amir, O., Bayes-Genis, A., Bozkurt, B., Butler, J., Chioncel, O., Mebazaa, A., Merino, J. L., Moura, B., Ponikowski, P., Seferovic, P., … Metra, M. (2025). Clinical management and therapeutic optimization of patients with heart failure with reduced ejection fraction and low blood pressure: A clinical consensus statement of the Heart Failure Association (HFA) of the ESC. European Journal of Heart Failure, 27(4), 707–722. https://doi.org/10.1002/ejhf.3618
Singh, A., & Mehta, Y. (2018). Heart failure with preserved ejection fraction (HFpEF): Implications for the anesthesiologists. Journal of Anaesthesiology Clinical Pharmacology, 34(2), 161. https://doi.org/10.4103/joacp.joacp_352_16
Reiterer, C., Kabon, B., Taschner, A., Graf, A., Adamowitsch, N., Horvath, K., Emler, D., Zotti, O., Hantakova, N., Hochreiter, B., Fraunschiel, M., Clement, T., & Fleischmann, E. (2025). Levosimendan for postoperative subclinical heart failure after noncardiac surgery: A randomized, double-blinded, phase III trial. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-60601-y
Fudim, M., Yaranov, D. M., Gupta, R., Letarte, L., Sears, S. F., Howard, B. G., Uriel, N., Raje, V., Mahmood, K., Pinney, S. P., Yeyha, A., Alam, A., Patel, P., Hicks, A., Bindra, A., Antoine, S. M., Feliberti, J., Rollins, A., Rao, V. N., … Sayed, A. (2025). Heart failure devices: Treatment options, underutilization, and a proposed trigger system for patient referral and evaluation. Journal of Cardiac Failure. https://doi.org/10.1016/j.cardfail.2025.08.019
Jhund, P. S., Talebi, A., Henderson, A. D., Claggett, B. L., Vaduganathan, M., Desai, A. S., Lam, C. S. P., Pitt, B., Senni, M., Shah, S. J., Voors, A. A., Zannad, F., Solomon, S. D., & McMurray, J. J. V. (2024). Mineralocorticoid receptor antagonists in heart failure: An individual patient level meta-analysis. The Lancet, 404(10458), 1119–1131. https://doi.org/10.1016/S0140-6736(24)01733-1
Eleyan, L., Gonnah, A. R., Farhad, I., Labib, A., Varia, A., Eleyan, A., Almehandi, A., Al-Naseem, A. O., & Roberts, D. H. (2025). Exercise training in heart failure: Current evidence and future directions. Journal of Clinical Medicine, 14(2), 359. https://doi.org/10.3390/jcm14020359
Alqahtani, A. S. (2025). Telehealth-based cardiac rehabilitation for heart failure: A systematic review of effectiveness, access, and patient-centred outcome. Medicina, 62(1), 25. https://doi.org/10.3390/medicina62010025
dos Santos Costa, A., Barbosa, C. B., Guizilini, S., Krainer, I. B., de Marqui Moraes, P. I., Rogério dos Santos, V., & Moreira, R. S. L. (2026). REVIVE-HF: Rehabilitation with immersive virtual reality and exercise in hospitalized patients with heart failure—A randomized controlled trial protocol. Trials, 27(1). https://doi.org/10.1186/s13063-026-09430-y
Herrmann, E. J., Raghavan, B., Tekeste, M., Mantzsch, K., Meybohm, P., & Assmus, B. (2024). Randomized pilot trial of pre‐ and postoperative heart failure nurse‐supported care in heart failure patients requiring noncardiac surgery—Feasibility and results. Clinical Cardiology, 47(6). https://doi.org/10.1002/clc.24304
Schmidt, C., Magalhães, S., Gois Basilio, P., Santos, C., Oliveira, M. I., Ferreira, J. P., Ribeiro, F., & Santos, M. (2025). Center- vs home-based cardiac rehabilitation in patients with heart failure. JACC: Heart Failure, 13(5), 695–706. https://doi.org/10.1016/j.jchf.2024.09.024
Eleyan, L., Gonnah, A. R., Farhad, I., Labib, A., Varia, A., Eleyan, A., Almehandi, A., Al-Naseem, A. O., & Roberts, D. H. (2025). Exercise training in heart failure: Current evidence and future directions. Journal of Clinical Medicine, 14(2), 359. https://doi.org/10.3390/jcm14020359
Mahmoodi, Z., Salari, A., Ahmadnia, Z., Roushan, Z. A., Gholipour, M., & Sedighinejad, A. (2025). Exercise-based cardiac rehabilitation for heart failure: Effects on echocardiographic parameters and functional capacity: A randomized clinical trial. Annals of Medicine & Surgery, 87(5), 2696–2701. https://doi.org/10.1097/MS9.0000000000003006
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Copyright (c) 2026 Paula Żak, Patrycja Pietraszkiewicz, Inez Michalska, Zuzanna Korbel, Katarzyna Pinkowska, Zuzanna Taciak, Filip Glista, Anna-Maria Grzeczka, Mikołaj Jaszowski, Agnieszka Dąbrowska, Weronika Nawrocka

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