COMPARISON OF FUNCTIONAL OUTCOMES AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
DOI:
https://doi.org/10.31435/ijitss.2(50).2026.5623Keywords:
ACL Reconstruction, Competitive Athletes, Bone–Patellar Tendon–Bone, Hamstring Tendon, Return To Sport, Graft Failure, Anterior Knee PainAbstract
Background. In competitive athletes undergoing anterior cruciate ligament reconstruction (ACLR), bone–patellar tendon–bone (BPTB) and hamstring tendon (HT) autografts are the most common options. Clinically meaningful differences likely appear in return-to-sport/performance, graft survival, knee stability, and donor-site morbidity.
Aim. To summarize 2021–2026 comparative evidence on BPTB versus HT in competitive/high-activity athletes after primary ACLR, focusing on return to sport/performance, patient-reported outcomes, function, stability, graft failure, and donor-site morbidity.
Materials and methods. Narrative literature review of PubMed and Scopus, including reviews, observational studies, and clinically relevant case series.
Results. Athlete-focused randomized and observational studies show generally similar outcomes between graft types at short- to mid-term follow-up. In professional/semi-professional soccer, RTS and knee-function scores were comparable at 2 years, but anterior knee pain was higher with BPTB (48.4%) than HT (22.6%). Large high-activity cohorts reported higher odds of return to preinjury activity with BPTB, though meta-analyses found no consistent difference across heterogeneous definitions. Instrumented laxity favored BPTB in athlete-focused syntheses and long-term cohorts, though surgical techniques may confound some findings. Several cohorts indicated higher ipsilateral graft failure/retear with HT in younger/high-risk athletes, while BPTB showed slower attainment of common early RTS strength/hop milestones.
Conclusions. In competitive/high-activity athletes, BPTB is associated with lower graft failure risk and modestly better stability, counterbalanced by higher anterior knee pain and potentially slower early functional recovery.
References
Bouju, S., Lauritzen, J. B., Journé, A., & Jørgensen, H. L. (2024). Return to sports after anterior cruciate ligament surgery with hamstring or patella tendon autograft: A systematic review. Danish Medical Journal. https://doi.org/10.61409/A09230599
Migliorini, F., Torsiello, E., & Trivellas, A. (2023). Bone-patellar tendon-bone versus two- and four-strand hamstring tendon autografts for ACL reconstruction in young adults: A Bayesian network meta-analysis. Scientific Reports, 13, 6883. https://doi.org/10.1038/s41598-023-33899-1
Bergeron, J. J., Sercia, Q. P., Drager, J., Pelet, S., & Belzile, E. L. (2022). Return to baseline physical activity after bone–patellar tendon–bone versus hamstring tendon autografts for anterior cruciate ligament reconstruction: A systematic review and meta-analysis of randomized controlled trials. The American Journal of Sports Medicine, 50(8), 2292–2303. https://doi.org/10.1177/03635465211017522
Guglielmetti, L. G. B., Salas, V. E. R., Jorge, P. B., et al. (2021). Prospective and randomized clinical evaluation of hamstring versus patellar tendon autograft for anterior cruciate ligament reconstruction in soccer players. Orthopaedic Journal of Sports Medicine, 9(9). https://doi.org/10.1177/23259671211028168
Rahardja, R., Love, H., Clatworthy, M. G., Monk, A. P., & Young, S. W. (2021). Higher rate of return to preinjury activity levels after anterior cruciate ligament reconstruction with a bone–patellar tendon–bone versus hamstring tendon autograft in high-activity patients: Results from the New Zealand ACL Registry. The American Journal of Sports Medicine, 49(13), 3488–3494. https://doi.org/10.1177/03635465211044142
Rahardja, R., Love, H., Clatworthy, M., & Young, S. (2023). Higher return to sport with patellar tendon autograft versus hamstring tendon autograft following anterior cruciate ligament reconstruction. Orthopaedic Proceedings, 105-B(Suppl. 3), 62–62. https://doi.org/10.1302/1358-992X.2023.3.062
Tomihara, T., Hashimoto, Y., Okazaki, S., Nishino, K., Taniuchi, M., Takigami, J., et al. (2024). Bone-patellar tendon-bone autograft is associated with a higher rate of return to preinjury levels of performance in high-level athletes than anterior cruciate ligament reconstruction using hamstring autograft. Knee Surgery, Sports Traumatology, Arthroscopy, 32, 1384–1395. https://doi.org/10.1002/ksa.12144
Connors, J. P., Cusano, A., Saleet, J., et al. (2025). Return to sport and graft failure rates after primary anterior cruciate ligament reconstruction with a bone–patellar tendon–bone versus hamstring tendon autograft: A systematic review and meta-analysis. The American Journal of Sports Medicine, 53(8), 1996–2006. https://doi.org/10.1177/03635465241295713
Steiner, Q., Walczak, B. E., Chumanov, E., Haraldsdottir, K., & Watson, A. M. (2024). Comparison of time needed to meet common rehabilitation milestones after anterior cruciate ligament reconstruction according to graft type. Orthopaedic Journal of Sports Medicine, 12(9). https://doi.org/10.1177/23259671241274687
Duchman, K., McCormick, E., Leary, S., An, Q., & Westermann, R. (2023). Poster 332: Return to sport, post-operative performance testing, and re-injury rates among athletes treated with hamstring, quadriceps, and patellar tendon autograft ACL reconstruction. Orthopaedic Journal of Sports Medicine, 11. https://doi.org/10.1177/2325967123S00300
Hetsroni, I., Mann, G., & Arami, E. (2024). Young men undergoing anterior cruciate ligament reconstruction with patellar tendon autograft and anteromedial drilling outperform at 5- to 10-year follow-up in terms of graft stability and activity levels compared to those undergoing reconstruction with hamstring autograft and transtibial drilling. Journal of ISAKOS, 9, 540–548. https://doi.org/10.1016/j.jisako.2024.04.001
Dudek, S., Koziak, W., Makieła, M., Bętkowska, A., Kornacka, A., Dudek, W., Szostak, K., Tomaka, R., Byra, A., & Makieła, M. (2025). Reconstruction of the anterior cruciate ligament in athletes: A review of methods and treatment outcomes. Quality in Sport, 39, 59286. https://doi.org/10.12775/QS.2025.39.59286
Tiplady, A., Love, H., Young, S. W., & Frampton, C. M. (2023). Comparative study of ACL reconstruction with hamstring versus patellar tendon graft in young women: A cohort study from the New Zealand ACL Registry. The American Journal of Sports Medicine, 51(3), 627–633. https://doi.org/10.1177/03635465221146299
Arida, C., Tsikrikas, C. G., Mastrokalos, D. S., et al. (2021). Comparison of bone-patella tendon-bone and four-strand hamstring tendon grafts for anterior cruciate ligament reconstruction: A prospective study. Cureus, 13(11), e19197. https://doi.org/10.7759/cureus.19197
Woźniak, K., Jung, M., Hedesz, P., Gardian-Baj, M., Jung, M., Żuk-Łapan, A., Doryń, A., Babula, E., Popczyńska, J., Włodarczyk, A., & Taras, A. (2024). The terror of athletes: Anterior cruciate ligament reconstruction, grafts and moden techniques. Journal of Education, Health and Sport, 57, 110–125. https://doi.org/10.12775/JEHS.2024.57.008
D’Ambrosi, R., Meena, A., Arora, E. S., Attri, M., Schäfer, L., & Migliorini, F. (2023). Reconstruction of the anterior cruciate ligament: A historical view. Annals of Translational Medicine, 11(10), 364. https://doi.org/10.21037/atm-23-87
Chung, K. S., Kim, J. H., Kong, D. H., Park, I., Kim, J. G., & Ha, J. K. (2022). An increasing trend in the number of anterior cruciate ligament reconstruction in Korea: A nationwide epidemiologic study. Clinics in Orthopedic Surgery, 14(2), 220–226. https://doi.org/10.4055/cios20276
Muscat, K., & Calleja, J. (2026). Hamstring tendon vs. bone-patellar tendon-bone grafts for primary anterior cruciate ligament reconstruction in football (soccer) players: A systematic review and meta-analysis. Cureus, 18(1), e100912. https://doi.org/10.7759/cureus.100912
Sim, K., Rahardja, R., Zhu, M., & Young, S. W. (2022). Optimal graft choice in athletic patients with anterior cruciate ligament injuries: Review and clinical insights. Open Access Journal of Sports Medicine, 13, 55–67. https://doi.org/10.2147/OAJSM.S340702
Thorolfsson, B., Svantesson, E., Snaebjornsson, T., et al. (2021). Adolescents have twice the revision rate of young adults after ACL reconstruction with hamstring tendon autograft: A study from the Swedish National Knee Ligament Registry. Orthopaedic Journal of Sports Medicine, 9(10), 232596712110388. https://doi.org/10.1177/23259671211038893
Brzoza, J., Werenkowicz, W., Boral, A., Kryś, D., Koczur, J., Górski, M., Pniok, W., Kurkiewicz, W., Bylica, K., & Czarnecki, B. (2025). Current trends in ACL reconstructions: A perspective review of recent literature. Journal of Education, Health and Sport, 82, 60477. https://doi.org/10.12775/JEHS.2025.82.60477
Mogoş, Ş., D’Ambrosi, R., Antonescu, D., & Stoica, I. (2021). Combined anterior cruciate ligament and anterolateral ligament reconstruction results in superior rotational stability compared with isolated anterior cruciate ligament reconstruction in high grade pivoting sport patients: A prospective randomized clinical trial. The Journal of Knee Surgery, 36(1), 54–61. https://doi.org/10.1055/s-0041-1729621
Wang, H., Zong, L., Hu, X., & Ao, Y. (2022). Efficacy of stem cell therapy for tendon graft ligamentization after anterior cruciate ligament reconstruction: A systematic review. Orthopaedic Journal of Sports Medicine, 10(6). https://doi.org/10.1177/23259671221098363
McCormick, E., Gao, Y., Geiger, K., et al. (2025). Associations between graft choice and return to sports after primary anterior cruciate ligament (ACL) reconstruction in athletes. Orthopaedic Journal of Sports Medicine, 13(10). https://doi.org/10.1177/23259671251369005
Ebert, J. R., Calvert, N. D., & Radic, R. (2024). A prospective randomized controlled trial investigating quadriceps versus hamstring tendon autograft in anterior cruciate ligament reconstruction. The American Journal of Sports Medicine, 52(3), 660–669. https://doi.org/10.1177/03635465231222279
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