TREATMENT METHODS FOR HPV-INDUCED WARTS: INTEGRATING MEDICAL THERAPIES, DIGITAL HEALTH TECHNOLOGIES, AND PUBLIC HEALTH IMPLICATIONS - A NARRATIVE REVIEW

Sylwia Hejna; Weronika Smutkiewicz; Weronika  Teterycz; Wiktoria Goździejewska; Łukasz Jaworek; Gabriela Zimka; Krystian Bjorgen; Lilianna Jasińska; Magdalena Roman; Martyna Lipiarz

doi:10.31435/ijitss.2(50).2026.5697

Authors

Sylwia Hejna Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0005-6313-3067
Weronika Smutkiewicz Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0007-4965-1903
Weronika Teterycz Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0000-7486-458X
Wiktoria Goździejewska Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0007-5302-1883
Łukasz Jaworek Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0007-8117-5644
Gabriela Zimka Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0005-3954-7307
Krystian Bjorgen Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0008-0225-7439
Lilianna Jasińska University of Warmia and Mazury in Olsztyn, Olsztyn, Poland https://orcid.org/0009-0006-0819-8922
Magdalena Roman Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0004-1261-180X
Martyna Lipiarz Cardinal Stefan Wyszyński University in Warsaw, Warsaw, Poland https://orcid.org/0009-0001-3124-9250

DOI:

https://doi.org/10.31435/ijitss.2(50).2026.5697

Keywords:

Human Papillomavirus, Cutaneous Warts, Teledermatology, Digital Health, Artificial Intelligence, Public Health

Abstract

Human papillomavirus (HPV)-induced warts are common dermatological conditions that impose a persistent clinical, psychosocial, and public-health burden despite their benign nature. This review aimed to synthesize current evidence on pharmacological and procedural treatments for HPV-induced warts while examining the growing role of digital health technologies and broader public-health considerations. A structured narrative review with systematic elements was conducted using PubMed, Scopus, and Web of Science, focusing primarily on English-language studies published between 2010 and March 2026. Evidence from clinical trials, systematic reviews, meta-analyses, guidelines, and selected high-quality observational studies was qualitatively synthesized. The findings indicate that conventional therapies, particularly salicylic acid and cryotherapy, remain central to management but are limited by variable efficacy, recurrence, and adherence challenges. Emerging immunotherapeutic approaches and selected procedural modalities, including laser therapy and photodynamic therapy, offer promise for resistant lesions. In parallel, teledermatology, mobile health applications, and artificial intelligence-based image analysis are expanding opportunities for early assessment, follow-up, and patient engagement. The review concludes that optimal management of HPV-induced warts requires a multidisciplinary strategy combining evidence-based treatment, technological innovation, and public-health awareness to improve access, adherence, equity, and patient well-being.

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