MANAGEMENT OF DIABETIC PATIENTS UNDERGOING ORAL SURGERY PROCEDURES: A NARRATIVE REVIEW
DOI:
https://doi.org/10.31435/ijitss.2(50).2026.5960Keywords:
Diabetes Mellitus, Oral Surgery, Perioperative Management, Tooth Extraction, Wound HealingAbstract
Introduction: Diabetes mellitus is a systemic metabolic disorder that requires careful perioperative management in oral and maxillofacial surgery.
Aim: To synthesize the current evidence on the perioperative management of diabetic patients undergoing oral surgery, with emphasis on preoperative assessment, glycemic control, medication adjustment, intraoperative precautions, and postoperative care.
Material and methods: This narrative review searched PubMed/MEDLINE and Google Scholar using terms related to diabetes mellitus, oral surgery, tooth extraction, perioperative management, glycemic control, HbA1c, antibiotic prophylaxis, wound healing, and postoperative complications. Twenty-three publications met the inclusion criteria.
Results: The literature shows that diabetes is a clinically relevant perioperative risk factor in oral surgery. Evidence on extraction healing is mixed: some studies found no significant effect of glycemic control on post-extraction healing, while others reported more unhealed sockets in patients with poorer glycemic control. The available evidence does not consistently support routine antibiotic prophylaxis for simple extractions.
Conclusions: Diabetes increases the perioperative risk in oral surgery, however, it is not a contraindication to treatment when patients are properly assessed and prepared. Individualized preoperative evaluation, glycemic control, careful surgical technique, and close postoperative follow-up are essential for safe management of these patients.
References
Crowley, K., O Scanaill, P., Hermanides, J., & Buggy, D. J. (2023). Current practice in the perioperative management of patients with diabetes mellitus: A narrative review. British Journal of Anaesthesia, 131(2), 242–252. https://doi.org/10.1016/j.bja.2023.02.039
Kayes, M. N., Prodhan, N. K., & Malik, R. H. (2014). Perioperative management of diabetes: A review. Delta Medical College Journal, 2(2), 71–76. https://doi.org/10.3329/dmcj.v2i2.20528
Nagni, M., Severino, M., Redi, L., Zizza, A., Pancrazi, G. L., Vavassori, E., et al. (2024). Possible complications in oral surgery and their management in patients affected by type 1 diabetes: Narrative review. Oral Implantology, 16(1), 32–37. https://doi.org/10.11138/oi16132-37
Cunha, C. E. S., Costa, M. R. C., Souza, M. F., Souza, D. S. M., Silva, I. L. R. R., Meneses, K. S., et al. (2024). Atendimento para cirurgia oral em pacientes diabéticos: Revisão narrativa da literatura. Uniciencias, 28(1), 44–49. https://doi.org/10.17921/1415-5141.2024v28n1p44-49
Allyn, S., Bentov, N., & Dillon, J. K. (2024). Perioperative optimization and management of the oral and maxillofacial surgical patient: A narrative review on updates in anticoagulation, hypertension and diabetes medications. Journal of Oral and Maxillofacial Surgery, 82(3), 364–375. https://doi.org/10.1016/j.joms.2023.11.015
Yoo, H. K., & Serafin, B. L. (2006). Perioperative management of the diabetic patient. Oral and Maxillofacial Surgery Clinics of North America, 18(2), 255–260. https://doi.org/10.1016/j.coms.2005.12.003
Al-Haddad, A., Hassona, Y., Silawi, A., & Al Kayed, A. (2021). A narrative review of diabetes mellitus: An update for dentists. Saudi Journal of Oral Sciences, 8(1), 2–8. https://doi.org/10.4103/sjos.SJOralSci_68_20
Bergman, S. A. (2007). Perioperative management of the diabetic patient. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 103(6), 731–737. https://doi.org/10.1016/j.tripleo.2006.11.029
Dhinsa, B. S., Khan, W. S., & Puri, A. (2010). Management of the patient with diabetes in the perioperative period. Journal of Perioperative Practice, 20(10), 364–367. https://doi.org/10.1177/175045891002001002
Todor, L., Rivis, M., Popovici, R. A., Cosoroaba, R. M., Todor, S. A., Roi, C., et al. (2022). Peculiarities of tooth extraction in patients with diabetes. Medicine in Evolution, 28(4), 483–491. https://doi.org/10.70921/medev.v28i4.1056
Vegh, D., Bencze, B., Banyai, D., Vegh, A., Rozsa, N., Nagy Dobo, C., et al. (2023). Preoperative HbA1c and blood glucose measurements in diabetes mellitus before oral surgery and implantology treatments. International Journal of Environmental Research and Public Health, 20(6), Article 4745. https://doi.org/10.3390/ijerph20064745
Cabon, J., Pejas, J., Zawilska, A., & Trzcionka, A. (2023). Diabetes in the context of dental treatment in an interdisciplinary approach. Journal of Education, Health and Sport, 13(5), 38–45. https://doi.org/10.12775/JEHS.2023.13.05.005
Aronovich, S., Skope, L. W., Kelly, J. P. W., & Kyriakides, T. C. (2010). The relationship of glycemic control to the outcomes of dental extractions. Journal of Oral and Maxillofacial Surgery, 68(12), 2955–2961. https://doi.org/10.1016/j.joms.2010.05.006
Huang, S., Dang, H., Huynh, W., Sambrook, P. J., & Goss, A. N. (2013). The healing of dental extraction sockets in patients with type 2 diabetes on oral hypoglycaemics: A prospective cohort. Australian Dental Journal, 58(1), 89–93. https://doi.org/10.1111/adj.12029
Chidambaram Shathviha, P., Sherlin, H., & Mathew, M. (2020). Healing of extraction socket in diabetic patients: A hospital based retrospective study. International Journal of Research in Pharmaceutical Sciences, 11(Suppl. 3). https://doi.org/10.26452/ijrps.v11ispl3.3448
Nityasri, A., & Prasad, K. (2025). Influence of glycemic control, use of adjuncts and antibiotic prophylaxis on socket healing in diabetics: A review of current clinical guidelines. International Journal of Scientific Research. https://doi.org/10.36106/ijsr/2808335
Yang, S., Li, Y., Liu, C., Wu, Y., Wan, Z., & Shen, D. (2022). Pathogenesis and treatment of wound healing in patients with diabetes after tooth extraction. Frontiers in Endocrinology, 13, Article 949535. https://doi.org/10.3389/fendo.2022.949535
Tkachuk, S. S., Tkachuk, O. V., Galagdina, A. A., Povar, M. A., & Perepeliuk, M. D. (2020). Current views on pathogenesis of oral complications with diabetes mellitus: Literature review. Journal of Education, Health and Sport, 10(7), 366–376. https://doi.org/10.12775/JEHS.2020.10.07.039
Sykara, M., Kourtesi, A., Mavrogiannis, M., Almpani, K., & Tzerbos, F. (2022). The necessity of administrating antibiotic prophylaxis to patients with diabetes mellitus prior to oral surgical procedures: A systematic review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 16(11), Article 102667. https://doi.org/10.1016/j.dsx.2022.102667
Taylor, G. W. (2003). The effects of periodontal treatment on diabetes. Journal of the American Dental Association, 134(1), 41–48. https://doi.org/10.14219/JADA.ARCHIVE.2003.0371
Ata-Ali, F., Melo, M., Cobo, T., Nagasawa, M. A., Shibli, J. A., & Ata-Ali, J. (2020). Does non-surgical periodontal treatment improve glycemic control? A comprehensive review of meta-analyses. Journal of the International Academy of Periodontology, 22(4), 205–222.
Grant, B., & Chowdhury, T. (2021). New guidance on the perioperative management of diabetes. Clinical Medicine, 21(4), e410–e411. https://doi.org/10.7861/clinmed.2021-0355
Goron, A. R., Connolly, C., Valdez-Sinon, A. N., Hesson, A., Helou, C., & Kirschen, G. W. (2024). Anti-hyperglycemic medication management in the perioperative setting: A review and illustrative case of an adverse effect of GLP-1 receptor agonist. Journal of Clinical Medicine, 13(20), Article 6259. https://doi.org/10.3390/jcm13206259
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Copyright (c) 2026 Emilia Miśkiewicz, Natalia Borek, Julia Gałązka, Ewa Stopa, Hanna Krupa, Zofia Wieczorek, Magdalena Kędrak, Dominik Stanisławski, Wiktoria Jabłońska-Trzosek, Jakub Pochwalski
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