OVERVIEW OF THE MAIN FUNGAL INFECTIONS IN HUMANS

Authors

DOI:

https://doi.org/10.31435/ijitss.3(51).2026.6233

Keywords:

Human Mycoses, Fungal Infections, Invasive Fungal Disease, Dermatophytosis, Candidiasis, Aspergillosis, Antifungal Resistance, Emerging Fungal Pathogens, Subcutaneous Mycoses, Endemic Mycoses

Abstract

Human fungal infections (mycoses) represent a rapidly growing public health concern worldwide. Although many fungi exist as environmental saprophytes or harmless commensals, a substantial number of species can cause disease ranging from superficial skin infections to severe invasive disease with high mortality. The global rise in immunocompromised patient populations, combined with increasing antifungal resistance, contributes to the expanding burden of fungal disease. This review summarizes the major categories of human mycoses, key etiological agents, clinical manifestations, diagnostic challenges, and current therapeutic strategies. Recent advances in diagnostics, antifungal development, and molecular epidemiology are discussed, with emphasis on emerging pathogens and evolving resistance profiles.

References

Brown, G. D., Denning, D. W., & Levitz, S. M. (2023). Tackling the emerging threat of fungal infections. Nature Reviews Microbiology, 21(10), 587–604.

Fisher, M. C., Gow, N. A., & Gurr, S. J. (2020). Human fungal pathogens: New insights and challenges. Cell Host & Microbe, 27(4), 451–464.

Hoenigl, M., et al. (2021). Invasive fungal diseases: Definitions and clinical considerations. The Lancet Infectious Diseases, 21(11), e396–e407.

Lass-Flörl, C. (2023). Epidemiology and management of invasive aspergillosis. Clinical Microbiology Reviews, 36(2), e00012–23.

Jeffery-Smith, A., et al. (2020). Emerging Candida auris: Epidemiology, antifungal resistance, and public health challenges. Journal of Antimicrobial Chemotherapy, 75(10), 2736–2744.

Wiederhold, N. P. (2023). Antifungal resistance: Current trends and future strategies. Current Opinion in Infectious Diseases, 36(4), 292–300.

Schwartz, I. S., & Govender, N. P. (2022). Global emergence of antifungal resistance in Candida and Aspergillus. Mycoses, 65(7), 635–646.

Thompson, G. R., III, et al. (2021). Endemic mycoses in North America: Current epidemiology and therapeutic approaches. Clinical Infectious Diseases, 72(7), e896–e903.

Katragkou, A., & Roilides, E. (2024). Advances in pediatric invasive fungal infections. Mycopathologia, 189(3), 451–462.

Scorzoni, L., de Paula e Silva, A. C., & Fusco-Almeida, A. M. (2021). New antifungal drugs and future perspectives. Frontiers in Microbiology, 12, 711.

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Published

2026-07-09

How to Cite

Rogowska-Borettini, K., Arciszewska, K., Padkowska, A., Pieniążek, J. M., Dobosz, M., Kajszczak, J., Romanowska, A., Biaduń-Mućko, W., Malmur, P. A., & Rak, A. (2026). OVERVIEW OF THE MAIN FUNGAL INFECTIONS IN HUMANS. International Journal of Innovative Technologies in Social Science, 1(3(51). https://doi.org/10.31435/ijitss.3(51).2026.6233