DEEP NECK INFECTIONS IN THE GERIATRIC POPULATION - LITERATURE REVIEW
DOI:
https://doi.org/10.31435/ijitss.3(51).2026.6530Keywords:
Deep Neck Infection, Dentistry, GeriatricsAbstract
Introduction and purpose: The aim of the study was to present and briefly discuss the causes of infections of deep neck tissues in geriatric patients. The issue of such factors as multiple diseases, surgical and dental procedures or pharmacotherapy in the geriatric population, which have a significant impact on the course of infection, was discussed.
Material and Methods: PubMed, ClinicalKey, and ClinicalTrials.gov were searched for material discussing the course of deep neck tissue infections in the senior population. The works and research from the years 2014-2026 were used, searching for terms such as "deep neck infection", "deep neck infection elderly", "deep neck infection geriatrics", "DNI elderly", "DNI geriatrics", "deep neck infection" age ". The aim was to show the course of DNI in the geriatric population and what mechanisms influence the course of the infections in this age group.
Results: Despite the fact that infections of deep neck tissues occur in all age groups, the geriatric population is particularly vulnerable to their aggressive course due to the presence of numerous risk factors, such as taking immunosuppressive drugs, lowered immunity or the presence of comorbidities.
Conclusions: There are problems with the diagnosis and treatment of DNI, especially in the elderly population, where the course of these infections may be different than in other age groups. Improper management may lead to health and life-threatening complications. The role of oral health prophylaxis is also very important, and it often does not reach geriatric patients sufficiently.
References
Lee, J. K., Kim, H. D., & Lim, S. C. (2007). Predisposing factors of complicated deep neck infection: An analysis of 158 cases. Yonsei Med J, 48(1), 55–62. https://doi.org/10.3349/ymj.2007.48.1.55
Ding, M. C., Hsu, C. M., Liu, S. Y., Lee, Y. C., Yang, Y. H., Liu, C. Y., Chang, G. H., Tsai, Y. T., Lee, L. A., Yang, P. R., Li, H. Y., & Tsai, M. S. (2021). Deep neck infection risk in patients with sleep apnea: Real-world evidence. Int J Environ Res Public Health, 18(6), 3191. https://doi.org/10.3390/ijerph18063191
Kim, S. Y., Park, I. H., Byun, C. S., Choi, H. G., Kwon, M. J., Kim, J. H., Kim, J. H., & Kim, C. W. (2024). Associations between peritonsillar abscess and deep neck infection in chronic periodontitis patients: Two nested case-control studies using a National Health Screening Cohort. J Clin Med, 13(8), 2166. https://doi.org/10.3390/jcm13082166
Sakarya, E. U., Kulduk, E., Gündoğan, O., Soy, F. K., Dündar, R., Kılavuz, A. E., Özbay, C., Eren, E., & İmre, A. (2015). Clinical features of deep neck infection: Analysis of 77 patients. Kulak Burun Bogaz Ihtis Derg, 25(2), 102–8. https://doi.org/10.5606/kbbihtisas.2015.76500
Treviño-Gonzalez, J. L., Santos-Santillana, K. M., Cortes-Ponce, J. R., Gonzalez-Andrade, B., & Morales-Del-Angel, J. A. (2023). Role of early extraction of odontogenic focus in deep neck infections. Med Oral Patol Oral Cir Bucal, 28(1), e25–e31. https://doi.org/10.4317/medoral.25536
Pucci, R., Cassoni, A., Di Carlo, D., Bartolucci, P., Della Monaca, M., Barbera, G., Di Cosola, M., Polimeni, A., & Valentini, V. (2023). Odontogenic-related head and neck infections: From abscess to mediastinitis: Our experience, limits, and perspectives-a 5-year survey. Int J Environ Res Public Health, 20(4), 3469. https://doi.org/10.3390/ijerph20043469
Tailor, B. V., Devakumar, H., Myuran, T., & Ioannidis, D. (2022). Parapharyngeal and floor-of-mouth abscess secondary to tonsillar phlegmon: A rare and unusual cause of Ludwig's angina. Clin Case Rep, 10(9), e6325. https://doi.org/10.1002/ccr3.6325
Maiese, A., Del Duca, F., Ghamlouch, A., Treves, B., Manetti, A. C., Napoletano, G., De Matteis, A., Dimattia, F., Wan, H., Pignataro, L., & La Russa, R. (2024). Sudden death: A practical autopsy approach to unexplained mediastinitis due to fatal untreated neck infections-a systematic review. Diagnostics (Basel), 14(11), 1150. https://doi.org/10.3390/diagnostics14111150
Martínez Pascual, P., Pinacho Martinez, P., Friedlander, E., Martin Oviedo, C., & Scola Yurrita, B. (2018). Peritonsillar and deep neck infections: A review of 330 cases. Braz J Otorhinolaryngol, 84(3), 305–310. https://doi.org/10.1016/j.bjorl.2017.03.008
Bal, K. K., Aslan, C., Gür, H., Bal, S. T., Ustun, R. O., & Unal, M. (2024). Deep neck infections mortal complications: Intrathoracic complications and necrotising fasciitis. World J Clin Cases, 12(30), 6383–6390. https://doi.org/10.12998/wjcc.v12.i30.6383
Mejias, C. D., Hubbard, D., Jeong, E., & Reddy, A. (2023). CT-guided transcutaneous drainage of peritonsillar abscess after failed ultrasound-guided drainage: A case report. Radiol Case Rep, 19(2), 654–660. https://doi.org/10.1016/j.radcr.2023.11.007
Sideris, G., Malamas, V., Tyrellis, G., Maragkoudakis, P., Delides, A., & Nikolopoulos, T. (2022). Ubi pus, ibi evacua: A review of 601 peritonsillar abscess adult cases. Ir J Med Sci, 191(4), 1849–1853. https://doi.org/10.1007/s11845-021-02796-9
Li, R. M., & Kiemeney, M. (2019). Infections of the neck. Emerg Med Clin North Am, 37(1), 95–107. https://doi.org/10.1016/j.emc.2018.09.003
Lin, Y., Gao, W., Yue, H., Chen, W., Liu, T., Ye, J., Cai, Q., Ye, F., He, L., Xie, X., Xiong, G., Wang, B., Pang, F., Li, P., Wu, J., Wang, B., Huang, J., Wen, W., & Lei, W. (2021). A novel risk score for the prediction of airway management in patients with deep neck space abscess: A multicenter retrospective cohort study. J Intensive Care, 9(1), 41. https://doi.org/10.1186/s40560-021-00554-8
Gao, W., Lin, Y., Yue, H., Chen, W., Liu, T., Ye, J., Cai, Q., Ye, F., He, L., Xie, X., Xiong, G., Wu, J., Wang, B., Wen, W., & Lei, W. (2022). Bacteriological analysis based on disease severity and clinical characteristics in patients with deep neck space abscess. BMC Infect Dis, 22(1), 280. https://doi.org/10.1186/s12879-022-07259-9
Lenka, S., Mir, S. A., Meher, R. K., Das, B. S., Swain, S. K., Nayak, B., Tripathy, S. K., & Dubey, D. (2026). Biological assessment of Coccinia grandis leaf and lupeol against β-lactam resistant Klebsiella pneumoniae through integrated in-silico and in-vitro studies. Sci Rep, 16(1), 11327. https://doi.org/10.1038/s41598-026-41907-3
Liu, C. F., Weng, S. F., Lin, Y. S., Lin, C. S., Lien, C. F., & Wang, J. J. (2013). Increased risk of deep neck infection among HIV-infected patients in the era of highly active antiretroviral therapy--a population-based follow-up study. BMC Infect Dis, 13, 183. https://doi.org/10.1186/1471-2334-13-183
Nour, Y. A., Hassan, M. H., Gaafar, A., & Eldaly, A. (2011). Deep neck infections of congenital causes. Otolaryngol Head Neck Surg, 144(3), 365–71. https://doi.org/10.1177/0194599810391629
Chang, G. H., Su, Y. C., Lin, K. M., Liu, C. Y., Yang, Y. H., Chang, P. J., Lin, M. H., Lee, C. P., Hsu, C. M., Tsai, Y. T., Wu, C. Y., & Tsai, M. S. (2020). Deep neck infection in systemic lupus erythematosus patients: Real-world evidence. Sci Rep, 10(1), 4133. https://doi.org/10.1038/s41598-020-61049-4
Hidaka, H., Yamaguchi, T., Hasegawa, J., Yano, H., Kakuta, R., Ozawa, D., Nomura, K., & Katori, Y. (2015). Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis. Head Neck, 37(10), 1536–46. https://doi.org/10.1002/hed.23776
Yuan, Q., Xing, X., Lu, Z., & Li, X. (2020). Clinical characteristics and risk factors of infection in patients with systemic lupus erythematosus: A systematic review and meta-analysis of observational studies. Semin Arthritis Rheum, 50(5), 1022–1039. https://doi.org/10.1016/j.semarthrit.2020.06.004
Jenifer, H. D., Boloor, V., & Belim, W. (2026). Strengthening geriatric oral health care through interprofessional education: Policy and practice implications. Front Dent Med, 7, 1784205. https://doi.org/10.3389/fdmed.2026.1784205
Tadjoedin, F. M., Adiatman, M., Lee, Y. Y. A., Banu, U. S., Tan, S. S. L., & Garg, V. (2025). Oral health and healthy aging: A multiregional review. JAR Life, 15, 100057. https://doi.org/10.1016/j.jarlif.2025.100057
Wongiam, N., Praditpornsilpa, K., & Vacharaksa, A. (2025). Comprehensive geriatric assessment for oral care in older adults: A focus group study. BMC Geriatr, 25(1), 232. https://doi.org/10.1186/s12877-025-05854-4
Isankova, O., Safronovs, J., Berke, K., & Taurmane, L. (2025). Zakażenia tkanek głębokich szyi. Przegląd 111 przypadków. Otolaryngol Pol, 79(1), 32–36. https://doi.org/10.5604/01.3001.0054.8465
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Copyright (c) 2026 Anna Bych, Zuzanna Kordyś-Wyrobek , Maciej Lazarek, Alicja Kamińska, Emilia Stachula-Mielczarek, Krzysztof Reszka

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