AI APPLICATIONS IN CT AND MRI IMAGING: CURRENT ADVANCES AND LIMITATIONS. A NARRATIVE REVIEW

Authors

DOI:

https://doi.org/10.31435/ijitss.2(50).2026.5103

Keywords:

Artificial Intelligence; Deep Learning; Medical Imaging; Computed Tomography; Magnetic Resonance Imaging; Image Reconstruction; Diagnostic Correctness; Multimodal Data Integration; Radiology Workflow; Clinical Decision Support

Abstract

Artificial intelligence (AI), primarily deep learning, is transforming medical imaging. Deep learning processes intricate data using layered neural networks. These techniques are also particularly applicable in computed tomography (CT), which utilizes X-rays to generate images, and magnetic resonance imaging (MRI), which utilizes magnetic fields and radio waves to generate detailed images. This review reviews advances made recently in AI detection, segmentation, classification, reconstruction, and the fusion of different data modalities in the CT and MRI fields. It also examines their impact in actual clinical practice. Studies show that deep learning models perform well in detecting lung nodules, brain tumors, and imaging of cardiovascular and abdominal organs. Besides this, AI methods based on reconstruction can shorten CT radiation doses and speed up MRI. And the best image quality is preserved.

Despite these results, obstacles remain that stop AI from being used for medical imaging. Most difficult problems encountered include limited testing on external data of different types at different institutions, the performance differences across different kinds of datasets, also deep learning models make decisions quite obscurely. Other persisting problems are how to make models more readable, how they can be integrated within clinical workflows, and regulations. The need to build more artificial intelligence that integrates imaging with clinical, genetic, and pathological data is an essential issue for future studies. Such methods could help predict better, personalize medicine. AI alone has potentially transformed radiology: from finding new ways to make diagnoses more efficient, standardizing interpretation of images and supporting clinical decision-making.

Nevertheless, AI ought to be viewed as a tool to aid radiologists — not a replacement. Such studies should be focused on testing AI in actual clinical environments, increasing the transparency of algorithms, and establishing standardized measurement methods for performance. These stages are required to securely and effectively embed AI in routine CT and MRI operations.

References

Abrigo, J. M., Ko, K. L., Chen, Q., Lai, B. M. H., Cheung, T. C. Y., Chu, W. C. W., & Yu, S. C. H. (2023). Artificial intelligence for detection of intracranial haemorrhage on head computed tomography scans: Diagnostic accuracy in Hong Kong. Hong Kong Medical Journal, 29(2), 112–120. https://doi.org/10.12809/hkmj209053

Alimiri Dehbaghi, H., Khoshgard, K., Sharini, H., & Khairabadi, S. J. (2024). Diagnosis of traumatic liver injury on computed tomography using machine learning algorithms and radiomics features: The role of artificial intelligence for rapid diagnosis in emergency rooms. Journal of Research in Medical Sciences, 29, 77. https://doi.org/10.4103/jrms.jrms_847_23

Aydoseli, A., Unal, T. C., Kardes, O., Doguc, O., Dolas, I., Adiyaman, A. E., Ortahisar, E., Silahtaroglu, G., Aras, Y., Sabanci, P. A., Sencer, S., & Sencer, A. (2022). An early warning system using machine learning for the detection of intracranial hematomas in the emergency trauma setting. Turkish Neurosurgery, 32(3), 459–465. https://doi.org/10.5137/1019-5149.JTN.35996-21.1

Chan, H. P., Samala, R. K., Hadjiiski, L. M., & Zhou, C. (2020). Deep learning in medical image analysis. Advances in Experimental Medicine and Biology, 1213, 3–21. https://doi.org/10.1007/978-3-030-33128-3_1

Chen, X., Wang, X., Zhang, K., Fung, K. M., Thai, T. C., Moore, K., Mannel, R. S., Liu, H., Zheng, B., & Qiu, Y. (2022). Recent advances and clinical applications of deep learning in medical image analysis. Medical Image Analysis, 79, 102444. https://doi.org/10.1016/j.media.2022.102444

Choi, R. Y., Coyner, A. S., Kalpathy-Cramer, J., Chiang, M. F., & Campbell, J. P. (2020). Introduction to machine learning, neural networks, and deep learning. Translational Vision Science & Technology, 9(2), 14. https://doi.org/10.1167/tvst.9.2.14

Fukumoto, W., Yamashita, Y., Kawashita, I., Higaki, T., Sakahara, A., Nakamura, Y., Awaya, Y., & Awai, K. (2025). External validation of the performance of commercially available deep-learning-based lung nodule detection on low-dose CT images for lung cancer screening in Japan. Japanese Journal of Radiology, 43(4), 634–640. https://doi.org/10.1007/s11604-024-01704-2

Grenier, P. A., Brun, A. L., & Mellot, F. (2022). The potential role of artificial intelligence in lung cancer screening using low-dose computed tomography. Diagnostics, 12(10), 2435. https://doi.org/10.3390/diagnostics12102435

Hafeez, Y., Memon, K., Al-Quraishi, M. S., Yahya, N., Elferik, S., & Ali, S. S. A. (2025). Explainable AI in diagnostic radiology for neurological disorders: A systematic review, and what doctors think about it. Diagnostics, 15(2), 168. https://doi.org/10.3390/diagnostics15020168

Hosny, A., Parmar, C., Quackenbush, J., Schwartz, L. H., & Aerts, H. J. W. L. (2018). Artificial intelligence in radiology. Nature Reviews Cancer, 18(8), 500–510. https://doi.org/10.1038/s41568-018-0016-5

Ji, M. T., Wang, R. R., Wang, Q., Li, H. S., & Zhao, Y. X. (2025). Feasibility study of “double-low” scanning protocol combined with artificial intelligence iterative reconstruction algorithm for abdominal computed tomography enhancement in patients with obesity. BMC Medical Imaging, 25(1), 276. https://doi.org/10.1186/s12880-025-01808-9

Kagiyama, N., Tokodi, M., Hathaway, Q. A., Arnaout, R., Davies, R., Dey, D., Duchateau, N., Fraser, A. G., Goto, S., Jamthikar, A. D., Lam, C. S. P., Oikonomou, E. K., Ouyang, D., Pandey, A., Poterucha, T. J., Raisi-Estabragh, Z., Strom, J. B., Zhang, Q., Yanamala, N., & Sengupta, P. P. (2026). PRIME 2.0: Proposed requirements for cardiovascular imaging-related multimodal-AI evaluation: An updated checklist. JACC: Cardiovascular Imaging, 19(2), 225–251. https://doi.org/10.1016/j.jcmg.2025.08.004

Kebaili, A., Lapuyade-Lahorgue, J., & Ruan, S. (2023). Deep learning approaches for data augmentation in medical imaging: A review. Journal of Imaging, 9(4), 81. https://doi.org/10.3390/jimaging9040081

Kitamura, F. C., & Topol, E. J. (2023). The initial steps of multimodal AI in radiology. Radiology, 309(1), e232372. https://doi.org/10.1148/radiol.232372

Lee, D. H., Lee, J. M., Lee, C. H., Afat, S., & Othman, A. (2024). Image quality and diagnostic performance of low-dose liver CT with deep learning reconstruction versus standard-dose CT. Radiology: Artificial Intelligence, 6(2), e230192. https://doi.org/10.1148/ryai.230192

Lipkova, J., Chen, R. J., Chen, B., Lu, M. Y., Barbieri, M., Shao, D., Vaidya, A. J., Chen, C., Zhuang, L., Williamson, D. F. K., Shaban, M., Chen, T. Y., & Mahmood, F. (2022). Artificial intelligence for multimodal data integration in oncology. Cancer Cell, 40(10), 1095–1110. https://doi.org/10.1016/j.ccell.2022.09.012

Lundervold, A. S., & Lundervold, A. (2019). An overview of deep learning in medical imaging focusing on MRI. Zeitschrift für Medizinische Physik, 29(2), 102–127. https://doi.org/10.1016/j.zemedi.2018.11.002

Maier, A., Syben, C., Lasser, T., & Riess, C. (2019). A gentle introduction to deep learning in medical image processing. Zeitschrift für Medizinische Physik, 29(2), 86–101. https://doi.org/10.1016/j.zemedi.2018.12.003

Martini, N., Aimo, A., Barison, A., Della Latta, D., Vergaro, G., Aquaro, G. D., Ripoli, A., Emdin, M., & Chiappino, D. (2020). Deep learning to diagnose cardiac amyloidosis from cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 22(1), 84. https://doi.org/10.1186/s12968-020-00690-4

Mohammadzadeh, I., Hajikarimloo, B., Niroomand, B., Faizi, N., Habibi, M. A., Mohammadzadeh, S., & Soltani, R. (2025). Artificial intelligence-based radiomic model in craniopharyngiomas: A systematic review and meta-analysis on diagnosis, segmentation, and classification. World Neurosurgery, 198, 124050. https://doi.org/10.1016/j.wneu.2025.124050

Podină, N., Gheorghe, E. C., Constantin, A., Cazacu, I., Croitoru, V., Gheorghe, C., Balaban, D. V., Jinga, M., Țieranu, C. G., & Săftoiu, A. (2025). Artificial intelligence in pancreatic imaging: A systematic review. United European Gastroenterology Journal, 13(1), 55–77. https://doi.org/10.1002/ueg2.12723

Ramedani, S., Kelesoglu, E., Stutzig, N., Von Tengg-Kobligk, H., Daneshvar Ghorbani, K., & Siebert, T. (2025). Quantification of training-induced alterations in body composition via automated machine learning analysis of MRI images in the thigh region: A pilot study in young females. Physiological Reports, 13(3), e70187. https://doi.org/10.14814/phy2.70187

Rueckel, J., Sperl, J. I., Kaestle, S., Hoppe, B. F., Fink, N., Rudolph, J., Schwarze, V., Geyer, T., Strobl, F. F., Ricke, J., Ingrisch, M., & Sabel, B. O. (2021). Reduction of missed thoracic findings in emergency whole-body computed tomography using artificial intelligence assistance. Quantitative Imaging in Medicine and Surgery, 11(6), 2486–2498. https://doi.org/10.21037/qims-20-1037

Seah, J., Brady, Z., Ewert, K., & Law, M. (2021). Artificial intelligence in medical imaging: Implications for patient radiation safety. The British Journal of Radiology, 94(1126), 20210406. https://doi.org/10.1259/bjr.20210406

Song, B., Leroy, A., Yang, K., Dam, T., Wang, X., Maurya, H., Pathak, T., Lee, J., Stock, S., Li, X. T., Fu, P., Lu, C., Toro, P., Chute, D. J., Koyfman, S., Saba, N. F., Patel, M. R., & Madabhushi, A. (2025). Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma. EBioMedicine, 114, 105663. https://doi.org/10.1016/j.ebiom.2025.105663

Tejani, A. S., Cook, T. S., Hussain, M., Sippel Schmidt, T., & O’Donnell, K. P. (2024). Integrating and adopting AI in the radiology workflow: A primer for standards and integrating the healthcare enterprise (IHE) profiles. Radiology, 311(3), e232653. https://doi.org/10.1148/radiol.232653

Terzis, R., Dratsch, T., Hahnfeldt, R., Basten, L., Rauen, P., Sonnabend, K., Weiss, K., Reimer, R., Maintz, D., Iuga, A. I., & Bratke, G. (2024). Five-minute knee MRI: An AI-based super resolution reconstruction approach for compressed sensing: A validation study on healthy volunteers. European Journal of Radiology, 175, 111418. https://doi.org/10.1016/j.ejrad.2024.111418

van Kempen, E. J., Post, M., Mannil, M., Witkam, R. L., Ter Laan, M., Patel, A., Meijer, F. J. A., & Henssen, D. (2021). Performance of machine learning algorithms for glioma segmentation of brain MRI: A systematic literature review and meta-analysis. European Radiology, 31(12), 9638–9653. https://doi.org/10.1007/s00330-021-08035-0

Wang, J., & Yin, L. (2024). CNN-based glioma detection in MRI: A deep learning approach. Technology and Health Care, 32(6), 4965–4982. https://doi.org/10.3233/THC-240158

Wang, T. W., Hong, J. S., Huang, J. W., Liao, C. Y., Lu, C. F., & Wu, Y. T. (2024). Systematic review and meta-analysis of deep learning applications in computed tomography lung cancer segmentation. Radiotherapy and Oncology, 197, 110344. https://doi.org/10.1016/j.radonc.2024.110344

Zhang, J., Lv, R., Chen, W., Du, G., Fu, Q., & Jiang, H. (2025). A novel residual network based on multidimensional attention and pinwheel convolution for brain tumor classification. Scientific Reports, 15(1), 31066. https://doi.org/10.1038/s41598-025-16564-7

Downloads

Published

2026-06-22

How to Cite

Cyrkler, A., Marzec, U., Wymoczył, K. ., Cieślak, N., Chodkowska, A. ., Dąbek, K., Czyżak, K. ., Rajca, E., Giza, A., & Giza, P. (2026). AI APPLICATIONS IN CT AND MRI IMAGING: CURRENT ADVANCES AND LIMITATIONS. A NARRATIVE REVIEW. International Journal of Innovative Technologies in Social Science, 4(2(50). https://doi.org/10.31435/ijitss.2(50).2026.5103

Most read articles by the same author(s)