TRANSURETHRAL RESECTION OR INCISION OF THE PROSTATE AS DEDICATED TREATMENT FOR BENIGN PROSTATIC HYPERPLASIA - A REVIEW ARTICLE BASED ON COMPARISON OF SCIENTIFIC RESEARCH

Agnieszka Mikłaszewicz; Rafał Siedlecki; Marta Góral; Dominik Fidorowicz; Daniel Sagan; Katarzyna Helena Sergiel; Emilia Torbacka; Aleksandra Irena  Skuza; Magda Downar-Zapolska; Katarzyna Bednarczuk

doi:10.31435/ijitss.2(50).2026.5629

Authors

Agnieszka Mikłaszewicz Pomeranian Medical University Hospital No. 1, Szczecin, Poland https://orcid.org/0009-0007-7423-6103
Rafał Siedlecki Independent Public Provincial Integrated Hospital in Szczecin – Zdunowo, Szczecin, Poland https://orcid.org/0009-0005-2653-2368
Marta Góral Independent Public Provincial Integrated Hospital in Szczecin – Zdunowo, Szczecin, Poland https://orcid.org/0009-0004-1063-897X
Dominik Fidorowicz Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0005-2184-4004
Daniel Sagan Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0007-8247-9842
Katarzyna Helena Sergiel Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0002-6627-9852
Emilia Torbacka Pomeranian Medical University Hospital No.2 – Szczecin, Poland https://orcid.org/0009-0001-4624-3564
Aleksandra Irena Skuza Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0000-3071-2015
Magda Downar-Zapolska Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0008-4646-0404
Katarzyna Bednarczuk Independent Public Provincial Integrated Hospital in Szczecin – Arkońska, Szczecin, Poland https://orcid.org/0009-0000-5207-6718

DOI:

https://doi.org/10.31435/ijitss.2(50).2026.5629

Keywords:

Benign Prostatic Hyperplasia (BPH); Benign Prostatic Enlargement (BPE); Transurethral Resection of The Prostate (TURP); Transurethral Incision of The Prostate Gland (TUIP); International Prostate Symptom Score (IPSS); Lower Urinary Tract Symptoms (LUTS); Retrograde Ejaculation; TURP Syndrome

Abstract

Introduction and objective: The prostate is a single glandular organ found only in men. Anatomically it is located below the urinary bladder, with the prostatic urethra passing through it. The function of the gland is to secrete fluid, which forms up to 30% of the semen. Physiologically, the dimensions of the organ are approximately 3 cm x 4 cm x 2.5 cm and the weight is 20-25 g. Due to its location, prostate enlargement can lead to constriction of the urethra, which in turn can lead to disturbances in micturition and sexual function.

Benign prostatic hyperplasia (BPH) is a common condition affecting men, whose prevalence increases with age. It often leads to lower urinary tract symptoms (LUST) - a group of urinary issues affecting storage (frequency, urgency, incontinence) and voiding (weak stream, hesitancy, straining). For many years, transurethral resection of the prostate (TURP) has remained the gold standard for BPH treatment. However, it is not the only available treatment method. Transurethral incision of the prostate gland (TUIP) is a less invasive method dedicated for less advanced prostatic hyperplasia.

This study aims to compare the efficacy and safety of TURP and TUIP based on literature review and comparison of scientific research.

Materials and methodology: The article was written based on a thorough analysis of scientific papers available on PubMed and Google Scholar, which serve as verified sources of information.

References

Lee, C.-L., & Kuo, H.-C. (2017). Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts. Tzu Chi Medical Journal, 29(2), 79–83. https://doi.org/10.4103/tcmj.tcmj_20_17

Foster, H. E., Barry, M. J., Dahm, P., Gandhi, M. C., Kaplan, S. A., & Kohler, T. S. (2018). Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA guideline. The Journal of Urology, 200(3), 612–619. https://doi.org/10.1016/j.juro.2018.05.048

Wei, H., Zhu, C., Huang, Q., Yang, J., Li, Y. T., Zhang, Y. G., Li, B. H., & Zi, H. (2025). Global, regional, and national burden of benign prostatic hyperplasia from 1990 to 2021 and projection to 2035. BMC Urology, 25, Article 34. https://doi.org/10.1186/s12894-025-01715-9

Orandi, A. (1990). Transurethral resection versus transurethral incision of the prostate. Urologic Clinics of North America, 17(3), 601–612. https://pubmed.ncbi.nlm.nih.gov/2375064/

Demirel, I., Ozer, A. B., Bayar, M. K., & Erhan, O. L. (2012). TURP syndrome and severe hyponatremia under general anaesthesia. BMJ Case Reports, 2012, Article bcr2012006899. https://doi.org/10.1136/bcr-2012-006899

Okeke, A. A., Lodge, R., Hinchliffe, A., Walker, A., Dickerson, D., & Gillatt, D. A. (2000). Ethanol-glycine irrigating fluid for transurethral resection of the prostate in practice. BJU International, 86(1), 43–46. https://doi.org/10.1046/j.1464-410x.2000.00733.x

Lourenco, T., Shaw, M., Fraser, C., MacLennan, G., N’Dow, J., Pickard, R., & Vale, L. (2010). The clinical effectiveness of transurethral incision of the prostate: A systematic review of randomised controlled trials. World Journal of Urology, 28(1), 23–32. https://doi.org/10.1007/s00345-009-0496-8

Riehmann, M., Knes, J. M., Heisey, D., Madsen, P. O., & Bruskewitz, R. C. (1995). Transurethral resection versus incision of the prostate: A randomized, prospective study. Urology, 45(5), 768–775. https://doi.org/10.1016/S0090-4295(99)80081-8

Hussain, M., Naz, K., Mustafa, G., Haneef, F., Gazder, T., Waleed, A., & Zafar, U. (2025). A comparative study of transurethral resection of the prostate (TURP) versus transurethral incision of the prostate (TUIP) in small-sized prostate glands with benign prostatic hyperplasia. Cureus, 17(6), Article e86848. https://doi.org/10.7759/cureus.86848

Tao, H., Jiang, Y. Y., Jun, Q., Ding, X., Jian, D. L., Jie, D., & Ping, Z. Y. (2016). Analysis of risk factors leading to postoperative urethral stricture and bladder neck contracture following transurethral resection of prostate. International Brazilian Journal of Urology, 42(2), 302–311. https://doi.org/10.1590/S1677-5538.IBJU.2014.0500

Robbani, A. G., Salam, M., & Islam, A. A. (2009). Transurethral resection (TURP) versus transurethral incision (TUIP) of the prostate for small sized benign prostatic hyperplasia: A prospective randomized study. TAJ: Journal of Teachers Association, 19(2), 50–56. https://doi.org/10.3329/taj.v19i2.3149