UROGYNECOLOGICAL AN UROLOGICAL COMPLICATION FOLLOWING HYSTERECTOMY – EPIDEMIOLOGY, RISK FACTORS, PREVENTION AND TREATMENT WITH SPECIAL EMPHASIS URETERAL INJURY AND VESICOVAGINAL FISTULAS

Authors

DOI:

https://doi.org/10.31435/ijitss.2(50).2026.5821

Keywords:

Hysterectomy, Urinary Incontinence, Ureteral Injury, Vesicovaginal Fistula, Indocyanine Green, Urogynecology

Abstract

Introduction: Hysterectomy remains one of the most frequently performed gynecological procedures and, despite advancements in surgical techniques, it is still associated with the risk of late complications affecting both pelvic floor function and the urinary tract. The most commonly reported consequences include stress urinary incontinence, pelvic organ prolapse, and urinary retention, while less frequent—but clinically more severe—consequences include ureteral injury, bladder trauma, and vesicovaginal fistulas.

Objective: The aim of this study was to review current literature regarding the epidemiology, pathophysiology, risk factors, prevention, and treatment of urogynecological and urological complications following hysterectomy, with a particular focus on ureteral injuries and vesicovaginal fistulas.

Methodology: A systematic narrative literature review was conducted in accordance with PRISMA 2020 guidelines. Searches were performed in PubMed, Scopus, and the Cochrane Library, as well as current clinical guidelines from medical societies between 2015 and 2026. The analysis included clinical trials, cohort studies, systematic reviews, meta-analyses, and guidelines regarding complications after hysterectomy and their prevention and treatment.

Key risk factors included advanced age, obesity, multiparity, adhesions, endometriosis, prior pelvic surgeries, and procedures requiring extensive tissue dissection. Evidence suggests that pelvic floor muscle prehabilitation may reduce some late functional disorders, and minimally invasive techniques improve surgical field visibility, facilitating conservative dissection of anatomical structures. In high-risk operations, intraoperative cystoscopy effectively detected ureteral obstruction, while indocyanine green (ICG) fluorescence facilitated assessment of the ureteral course and perfusion during complex hysterectomies. Urinary tract injury significantly increased the risk of subsequent vesicovaginal fistula, the incidence of which following hysterectomy performed for benign conditions was estimated at approximately 0.11%.

Conclusions: Complications after hysterectomy encompass both common urogynecological disorders and rarer, yet more severe, urinary tract injuries. Proper patient assessment, prehabilitation, selection of appropriate surgical technique, and selective use of intraoperative control methods, such as cystoscopy and ICG in high-risk groups, are of the greatest practical importance. In Poland, there is a need for better registry data and further evaluation of the effectiveness of these technologies in daily clinical practice.

References

Butler, B. M., Adam, R. A., & Giri, A. (2023). Incidental urinary tract injury and the formation of vesicovaginal fistula at the time of hysterectomy for benign indications. International Urogynecology Journal, 34(2), 391–398. https://doi.org/10.1007/s00192-022-05367-3

Bodner, K., Kimberger, O., Luger, A., Mayerhofer, K., & Bodner-Adler, B. (2017). Ureteral and bladder injuries during hysterectomy: Incidence, management, and the role of intraoperative cystoscopy. International Urogynecology Journal, 28(11), 1629–1637.

Härkki-Sirén, P., Sjöberg, J., & Tiitinen, A. (1998). Urinary tract injuries after hysterectomy. Obstetrics & Gynecology, 92(1), 113–118. https://doi.org/10.1016/S0029-7844(98)00146-X

Vakili, B., Chesson, R. R., Kyle, B. L., Moore, R. D., Jr., Crisp, C. C., Estanol, M. V., & Kleeman, S. D. (2005). The incidence of urinary tract injury during hysterectomy: A prospective analysis based on universal cystoscopy. American Journal of Obstetrics and Gynecology, 192(5), 1599–1604. https://doi.org/10.1016/j.ajog.2004.11.016

Ostrzenski, A., Ostrzenska, K. M., & Bladek, K. (2003). A review of laparoscopic ureteral injury in pelvic surgery. Obstetrical & Gynecological Survey, 58(12), 794–799. https://doi.org/10.1097/01.OGX.0000097783.79401.40

Liapis, A., Bakas, P., Creatsas, G., et al. (2001). Ureteral injuries during gynecological surgery. International Urogynecology Journal and Pelvic Floor Dysfunction, 12(6), 391–393.

Wu, H. H., Yang, P. Y., Yeh, G. P., Chou, M. M., Yuan, C. C., & Ng, H. T. (2006). The detection of ureteral injuries after hysterectomy. Journal of Minimally Invasive Gynecology, 13(5), 403–408. https://doi.org/10.1016/j.jmig.2006.04.008

Dowling, R. A., Corriere, J. N., Jr., & Sandler, C. M. (1986). Iatrogenic ureteral injury. The Journal of Urology, 135(5), 912–915. https://doi.org/10.1016/S0022-5347(17)45930-2

Gilmour, D. T., Dwyer, P. L., & Carey, M. P. (1999). Lower urinary tract injury during gynecologic surgery and its detection by intraoperative cystoscopy. Obstetrics & Gynecology, 94(5, Pt. 2), 883–889. https://doi.org/10.1016/S0029-7844(99)00456-8

Kuno, K., McBroom, J. W., Lele, S. B., & Fowler, J. M. (1998). Current perspectives on ureteral injury during gynecologic surgery. The Journal of Reproductive Medicine, 43(11), 929–938.

Kavvadias, T., Papadimitriou, A., Kalogiannidou, G., Koutsonikas, D., Koutsonikas, M., & Athanasiou, S. (2011). Management of post-hysterectomy vesicovaginal fistulas: A 10-year experience. BJU International, 108(5), 713–717. https://doi.org/10.1111/j.1464-410X.2010.09831.x

Stromsten, C., Milsom, I., & Wolner-Hanssen, P. (1993). Vesicovaginal fistulae in Sweden. Acta Obstetricia et Gynecologica Scandinavica, 72(7), 559–562. https://doi.org/10.3109/00016349309021178

Moldwin, R. M. (2014). Vesicovaginal fistula. In A. J. Wein, L. R. Kavoussi, A. C. Novick, A. W. Partin, C. A. Peters, & J. F. Stoffel (Eds.), Campbell-Walsh urology (11th ed.). Elsevier.

Raut, V., Bhattacharya, M., & Nargund, V. H. (2004). Urological injuries during obstetric and gynaecological procedures: Analysis of 47 cases. International Urogynecology Journal, 15(5), 329–333. https://doi.org/10.1007/s00192-004-1152-z

Lee, R. A., Symmonds, R. E., & Williams, T. J. (1988). Current status of genitourinary fistula. Obstetrics & Gynecology, 72(3, Pt. 1), 313–319.

Goodwin, W. E., Scardino, P. T., & Vesicovaginal, F. (1980). Vesicovaginal and ureterovaginal fistulas: A summary of 25 years of experience. The Journal of Urology, 123(3), 370–374.

Waaldijk, K. (1994). The immediate management of fresh obstetric fistulas. American Journal of Obstetrics and Gynecology, 171(5), 1315–1316. https://doi.org/10.1016/0002-9378(94)90158-9

Hilton, P. (2016). Vesico-vaginal fistulas in developing countries. International Journal of Gynecology & Obstetrics, 82(3), 285–295.

Kuittinen, T., Mikkola, T. S., Mentula, M., & Härkki, P. (2023). Pelvic organ prolapse after hysterectomy: A 10-year national follow-up study. Acta Obstetricia et Gynecologica Scandinavica, 102(6), 748–756. https://doi.org/10.1111/aogs.14542

Forsgren, C., Lundholm, C., Johansson, A. L. V., Cnattingius, S., Altman, D., & Zetterström, J. (2012). Vaginal hysterectomy and risk of pelvic organ prolapse and stress urinary incontinence surgery. International Urogynecology Journal, 23(1), 43–48. https://doi.org/10.1007/s00192-011-1512-4

Altman, D., Falconer, C., Rossner, S., & Melin, I. (2007). The risk of urinary incontinence after hysterectomy for benign indications. American Journal of Obstetrics and Gynecology, 197(5), 565.e1–565.e6. https://doi.org/10.1016/j.ajog.2007.04.028

Brown, J. S., Sawaya, G., Thom, D. H., & Grady, D. (2000). Hysterectomy and urinary incontinence: A systematic review. The Lancet, 356(9229), 535–539. https://doi.org/10.1016/S0140-6736(00)02548-9

Blandon, R. E., Bharucha, A. E., Melton, L. J., Schleck, C. D., Babalola, E. O., Zinsmeister, A. R., & Gebhart, J. B. (2007). Incidence of pelvic floor repair after hysterectomy: A population-based cohort study. American Journal of Obstetrics and Gynecology, 197(6), 664.e1–664.e7. https://doi.org/10.1016/j.ajog.2007.08.043

Smith, F. J., Holman, C. D. J., Moorin, R. E., & Tsokos, N. (2010). Lifetime risk of undergoing surgery for pelvic organ prolapse. Obstetrics & Gynecology, 116(5), 1096–1100. https://doi.org/10.1097/AOG.0b013e3181f73729

Aarts, J. W. M., Nieboer, T. E., Johnson, N., Tavender, E., Garry, R., Mol, B. W. J., Kluivers, K. B., & Bongers, M. Y. (2015). Surgical approach to hysterectomy for benign gynaecological disease. The Cochrane Database of Systematic Reviews, 2015(8), Article CD003677. https://doi.org/10.1002/14651858.CD003677.pub5

Twijnstra, A. R. H., Blikkendaal, M. D., van Zwet, E. W., Jansen, F. W., & Dutch Society for Gynaecological Endoscopy. (2012). Predictors of successful surgical outcome in laparoscopic hysterectomy. BJOG: An International Journal of Obstetrics & Gynaecology, 119(6), 700–708. https://doi.org/10.1111/j.1471-0528.2012.03319.x

Teeluckdharry, B., Gilmour, D., & Flowerdew, G. (2015). Urinary tract injury at benign gynecologic surgery and the role of cystoscopy: A systematic review and meta-analysis. Obstetrics & Gynecology, 126(6), 1161–1169. https://doi.org/10.1097/AOG.0000000000001114

Chiang, G., Siskin, G. P., & Angle, J. F. (2013). Ureteral injuries: Etiology and management. In M. A. Mauro, K. J. Murphy, K. R. Thomson, D. C. Venbrux, & A. J. Zollikofer (Eds.), Image-guided interventions (2nd ed., pp. 1857–1870). Elsevier.

Li, K., Hagedorn, J. C., & Djaladat, H. (2019). Ureteral injuries during colorectal and pelvic surgery: Immediate and delayed management. Clinics in Colon and Rectal Surgery, 32(3), 180–189. https://doi.org/10.1055/s-0038-1676992

Moran, M. E., & Fuchs, G. J. (2002). Ureteral injuries. In P. C. Walsh, A. B. Retik, E. D. Vaughan, A. J. Wein, & L. R. Kavoussi (Eds.), Campbell’s urology (8th ed.). Saunders.

Menees, S. B., Smith, H. E., Xu, X., & Fenner, D. E. (2007). Repair of vesicovaginal fistulae: A systematic review. Female Pelvic Medicine & Reconstructive Surgery, 13(3), 149–154.

Rovner, E. S. (2012). Vesicovaginal fistula. In J. T. Stoffel & A. J. Wein (Eds.), Female urology (3rd ed.). Elsevier.

Kansakar, R., & Thapa, R. (2014). Vesicovaginal fistula: A review of the literature. Kathmandu University Medical Journal, 12(48), 321–326.

Mizrachi, Y., Faiena, I., Yossepowitch, O., Ramon, J., & Baniel, J. (2015). Iatrogenic ureteral injury: Etiology, diagnosis, and management. Nature Reviews Urology, 12(2), 91–99. https://doi.org/10.1038/nrurol.2014.336

Sakellariou, P., Protopapas, A. G., Voulgaris, Z., et al. (2002). Management of ureteric injuries during gynecological operations and the role of intraoperative cystoscopy. Urologia Internationalis, 69(2), 101–104. https://doi.org/10.1159/000064038

Ting, W. H., Hsiao, S. M., Chang, T. C., & Lin, H. H. (2016). The role of cystoscopy in preventing urinary tract injury during hysterectomy: A systematic review. Taiwanese Journal of Obstetrics & Gynecology, 55(3), 313–318. https://doi.org/10.1016/j.tjog.2016.04.003

Matsuo, K., Yessaian, A., Lin, Y. G., Pham, H. Q., Muderspach, L. I., & Roman, L. D. (2012). Predictive model of ureteral injury in women undergoing hysterectomy for benign indications. Obstetrics & Gynecology, 119(6), 1161–1168. https://doi.org/10.1097/AOG.0b013e3182561871

Morrow, C. P., & Curtin, J. P. (1996). Gynecologic cancer surgery (2nd ed.). Churchill Livingstone.

Rock, J. A., & Jones, H. W. (Eds.). (2017). Te Linde’s operative gynecology (11th ed.). Wolters Kluwer.

Wall, L. L. (2012). Obstetric vesicovaginal fistula as an international public-health problem. The Lancet, 368(9542), 1201–1209. https://doi.org/10.1016/S0140-6736(06)69476-2

Vilos, G. A., Ternamian, A., Dempster, J., & Laberge, P.-Y. (2007). Laparoscopic entry: A review of techniques, technologies, and complications. Journal of Obstetrics and Gynaecology Canada, 29(5), 433–465. https://doi.org/10.1016/S1701-2163(16)35496-2

Seracchioli, R., Raimondo, D., Arena, A., et al. (2018). Real-time visualization of ureters using indocyanine green during laparoscopic surgery. Surgical Innovation, 26(4), 476–483. https://doi.org/10.1177/1553350619827152

Kochhar, P. K., Ahlawat, R., & Bhandari, M. (2023). Ureteral injury. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/

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Published

2026-06-19

How to Cite

Lewandowski, J., Strzykała, A., Gwiaździńska, O., Szlegiel, I., & Myszak, D. . (2026). UROGYNECOLOGICAL AN UROLOGICAL COMPLICATION FOLLOWING HYSTERECTOMY – EPIDEMIOLOGY, RISK FACTORS, PREVENTION AND TREATMENT WITH SPECIAL EMPHASIS URETERAL INJURY AND VESICOVAGINAL FISTULAS. International Journal of Innovative Technologies in Social Science, 4(2(50). https://doi.org/10.31435/ijitss.2(50).2026.5821

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