ARTIFICIAL INTELLIGENCE IN DERMATOLOGY: OPPORTUNITIES, LIMITATIONS, ETHICAL CHALLENGES AND HEALTH EQUITY – A NARRATIVE REVIEW
DOI:
https://doi.org/10.31435/ijitss.3(51).2026.6375Keywords:
Artificial Intelligence, Dermatology, Health Equity, Skin Cancer, Teledermatology, Deep LearningAbstract
Background: Artificial intelligence (AI) has become a promising tool in dermatology that could improve diagnostic accuracy, optimize clinical workflows, and expand access to dermatological care. Recent advances in machine learning and deep learning have enabled the development of highly accurate image-analysis systems, particularly for the diagnosis of skin lesions. However, the implementation of AI in clinical practice is accompanied by important ethical, legal, and equity-related challenges.
Objective: This narrative review aims to summarize the current evidence regarding the applications of artificial intelligence in dermatology, with particular emphasis on its potential to improve healthcare accessibility, support teledermatology, and promote health equity while addressing existing limitations and ethical concerns.
Methods: A narrative review of the literature was conducted using PubMed, PubMed Central, and Google Scholar. Peer-reviewed articles published in English between 2017 and 2025 were included. The literature was selected using keywords related to artificial intelligence, dermatology, skin cancer, teledermatology, and health equity.
Results: The reviewed literature demonstrates that AI has achieved high diagnostic performance in the recognition of various skin diseases, particularly malignant skin lesions, and may significantly improve access to dermatological services through teledermatology and decision-support systems. Nevertheless, challenges including algorithmic bias, limited representation of diverse skin phototypes in training datasets, data privacy concerns, and insufficient regulatory frameworks remain substantial barriers to widespread implementation.
Conclusions: Artificial intelligence has the potential to transform dermatological care by enhancing diagnostic efficiency and improving healthcare accessibility. However, its successful integration into clinical practice requires diverse and representative datasets, robust ethical and legal standards, and continued human oversight to ensure safe, equitable, and patient-centered healthcare.
References
Esteva, A., Kuprel, B., Novoa, R. A., Ko, J., Swetter, S. M., Blau, H. M., & Thrun, S. (2017). Dermatologist-level classification of skin cancer with deep neural networks. Nature, 542, 115–118. https://doi.org/10.1038/nature21056
Han, S. S., Park, G. H., Lim, W., Kim, M. S., Na, J. I., Park, I., & Chang, S. E. (2018). Deep neural networks show an equivalent and often superior performance to dermatologists in onychomycosis diagnosis: Automatic construction of onychomycosis datasets by region-based convolutional deep neural network. PLOS ONE, 13(1), e0191493. https://doi.org/10.1371/journal.pone.0191493
Han, S. S., Park, I., Chang, S. E., Lim, W., Kim, M. S., Park, G. H., Chae, J. B., Huh, C. H., & Na, J. I. (2020). Augmented intelligence dermatology: Deep neural networks empower medical professionals in diagnosing skin cancer and predicting treatment options for 134 skin disorders. Journal of Investigative Dermatology, 140(9), 1753–1761. https://doi.org/10.1016/j.jid.2020.01.019
Liopyris, K., Gregoriou, S., Dias, J., & Stratigos, A. J. (2022). Artificial intelligence in dermatology: Challenges and perspectives. Dermatology and Therapy, 12(12), 2637–2651. https://doi.org/10.1007/s13555-022-00833-8
Zbrzezny, A. M., & Krzywicki, T. (2025). Artificial intelligence in dermatology: A review of methods, clinical applications, and perspectives. Applied Sciences, 15(14), 7856. https://doi.org/10.3390/app15147856
Jutzi, T. B., Krieghoff-Henning, E. I., Holland-Letz, T., Utikal, J. S., Hauschild, A., Schadendorf, D., Sondermann, W., Fröhling, S., Hekler, A., Schmitt, M., Maron, R. C., & Brinker, T. J. (2020). Artificial intelligence in skin cancer diagnostics: The patients’ perspective. Frontiers in Medicine, 7, 233. https://doi.org/10.3389/fmed.2020.00233
Tschandl, P., Rosendahl, C., & Kittler, H. (2018). The HAM10000 dataset, a large collection of multi-source dermatoscopic images of common pigmented skin lesions. Scientific Data, 5, 180161. https://doi.org/10.1038/sdata.2018.161
Haggenmüller, S., Maron, R. C., Hekler, A., Utikal, J. S., Barata, C., Barnhill, R. L., Beltraminelli, H., Berking, C., Betz-Stablein, B., Blum, A., Braun, S. A., Carr, R., Combalia, M., Fernandez-Figueras, M. T., Ferrara, G., Fraitag, S., French, L. E., Gellrich, F. F., Ghoreschi, K., Goebeler, M., . . . Brinker, T. J. (2021). Skin cancer classification via convolutional neural networks: Systematic review of studies involving human experts. European Journal of Cancer, 156, 202–216. https://doi.org/10.1016/j.ejca.2021.06.049
Salinas, M. P., Sepúlveda, J., Hidalgo, L., Peirano, D., Morel, M., Uribe, P., Rotemberg, V., Briones, J., Mery, D., & Navarrete-Dechent, C. (2024). A systematic review and meta-analysis of artificial intelligence versus clinicians for skin cancer diagnosis. NPJ Digital Medicine, 7(1), 125. https://doi.org/10.1038/s41746-024-01103-x
Tschandl, P., Rinner, C., Apalla, Z., Argenziano, G., Codella, N., Halpern, A., Janda, M., Lallas, A., Longo, C., Malvehy, J., Paoli, J., Puig, S., Rosendahl, C., Soyer, H. P., Zalaudek, I., & Kittler, H. (2020). Human-computer collaboration for skin cancer recognition. Nature Medicine, 26(8), 1229–1234. https://doi.org/10.1038/s41591-020-0942-0
Liu, Y., Jain, A., Eng, C., Way, D. H., Lee, K., Bui, P., Kanada, K., de Oliveira Marinho, G., Gallegos, J., Gabriele, S., Gupta, V., Singh, N., Natarajan, V., Hofmann-Wellenhof, R., Corrado, G. S., Peng, L. H., Webster, D. R., Ai, D., Huang, S. J., . . . Coz, D. (2020). A deep learning system for differential diagnosis of skin diseases. Nature Medicine, 26(6), 900–908. https://doi.org/10.1038/s41591-020-0842-3
Du-Harpur, X., Watt, F. M., Luscombe, N. M., & Lynch, M. D. (2020). What is AI? Applications of artificial intelligence to dermatology. British Journal of Dermatology, 183(3), 423–430. https://doi.org/10.1111/bjd.18880
Daneshjou, R., Vodrahalli, K., Novoa, R. A., Jenkins, M., Liang, W., Rotemberg, V., Ko, J., Swetter, S. M., Bailey, E. E., Gevaert, O., Mukherjee, P., Phung, M., Yekrang, K., Fong, B., Sahasrabudhe, R., Allerup, J. A. C., Okata-Karigane, U., Zou, J., & Chiou, A. S. (2022). Disparities in dermatology AI performance on a diverse, curated clinical image set. Science Advances, 8(32), eabq6147. https://doi.org/10.1126/sciadv.abq6147
Adamson, A. S., & Smith, A. (2018). Machine learning and health care disparities in dermatology. JAMA Dermatology, 154(11), 1247–1248. https://doi.org/10.1001/jamadermatol.2018.2348
Fliorent, R., Fardman, B., Podwojniak, A., Javaid, K., Tan, I. J., Ghani, H., Truong, T. M., Rao, B., & Heath, C. (2024). Artificial intelligence in dermatology: Advancements and challenges in skin of color. International Journal of Dermatology, 63(4), 455–461. https://doi.org/10.1111/ijd.17076
Kamulegeya, L., Bwanika, J., Okello, M., Rusoke, D., Nassiwa, F., Lubega, W., Musinguzi, D., & Börve, A. (2023). Using artificial intelligence on dermatology conditions in Uganda: A case for diversity in training data sets for machine learning. African Health Sciences, 23(2), 753–763. https://doi.org/10.4314/ahs.v23i2.86
Gordon, E. R., Trager, M. H., Kontos, D., Weng, C., Geskin, L. J., Dugdale, L. S., & Samie, F. H. (2024). Ethical considerations for artificial intelligence in dermatology: A scoping review. British Journal of Dermatology, 190(6), 789–797. https://doi.org/10.1093/bjd/ljae040
Minssen, T., Gerke, S., Aboy, M., Price, N., & Cohen, G. (2020). Regulatory responses to medical machine learning. Journal of Law and the Biosciences, 7(1), lsaa002. https://doi.org/10.1093/jlb/lsaa002
Topol, E. J. (2019). High-performance medicine: The convergence of human and artificial intelligence. Nature Medicine, 25(1), 44–56. https://doi.org/10.1038/s41591-018-0300-7
Floridi, L., Cowls, J., Beltrametti, M., Chatila, R., Chazerand, P., Dignum, V., Luetge, C., Madelin, R., Pagallo, U., Rossi, F., Schafer, B., Valcke, P., & Vayena, E. (2018). AI4People—An ethical framework for a good AI society: Opportunities, risks, principles, and recommendations. Minds and Machines, 28(4), 689–707. https://doi.org/10.1007/s11023-018-9482-5
Börve, A., Dahlén Gyllencreutz, J., Terstappen, K., Johansson Backman, E., Aldenbratt, A., Danielsson, M., Gillstedt, M., Sandberg, C., & Paoli, J. (2015). Smartphone teledermoscopy referrals: A novel process for improved triage of skin cancer patients. Acta Dermato-Venereologica, 95(2), 186–190. https://doi.org/10.2340/00015555-1906
Chen, X., Zhou, Z., Ding, H., Zheng, H., & Ge, Y. (2025). Transforming aesthetic dermatology: The role of artificial intelligence in skin health. Dermatology and Therapy, 15(8), 1999–2013. https://doi.org/10.1007/s13555-025-01459-2
Verghese, A., Shah, N. H., & Harrington, R. A. (2018). What this computer needs is a physician: Humanism and artificial intelligence. JAMA, 319(1), 19–20. https://doi.org/10.1001/jama.2017.19198
Tschandl, P., Rosendahl, C., Akay, B. N., Argenziano, G., Blum, A., Braun, R. P., Cabo, H., Gourhant, J. Y., Kreusch, J., Lallas, A., Lapins, J., Marghoob, A., Menzies, S., Neuber, N. M., Paoli, J., Rabinovitz, H. S., Rinner, C., Scope, A., Soyer, H. P., . . . Kittler, H. (2019). Expert-level diagnosis of nonpigmented skin cancer by combined convolutional neural networks. JAMA Dermatology, 155(1), 58–65. https://doi.org/10.1001/jamadermatol.2018.4378
De, A., Sarda, A., Gupta, S., & Das, S. (2020). Use of artificial intelligence in dermatology. Indian Journal of Dermatology, 65(5), 352–357. https://doi.org/10.4103/ijd.IJD_418_20
Muñoz-López, C., Ramírez-Cornejo, C., Marchetti, M. A., Han, S. S., Del Barrio-Díaz, P., Jaque, A., Uribe, P., Majerson, D., Curi, M., Del Puerto, C., Reyes-Baraona, F., Meza-Romero, R., Parra-Cares, J., Araneda-Ortega, P., Guzmán, M., Millán-Apablaza, R., Nuñez-Mora, M., Liopyris, K., Vera-Kellet, C., & Navarrete-Dechent, C. (2021). Performance of a deep neural network in teledermatology: A single-centre prospective diagnostic study. Journal of the European Academy of Dermatology and Venereology, 35(2), 546–553. https://doi.org/10.1111/jdv.16979
Moulaei, K., Akhlaghpour, S., & Fatehi, F. (2025). Patient consent for the secondary use of health data in artificial intelligence (AI) models: A scoping review. International Journal of Medical Informatics, 198, 105872. https://doi.org/10.1016/j.ijmedinf.2025.105872
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Copyright (c) 2026 Adela Dzwonkowska, Jakub Dzwonkowski, Alicja Kozłowska, Karolina Przybysz, Jarosław Rachoń, Luiza Stadnik, Nicol Szerenos, Daria Trocka, Natalia Woroniecka, Natalia Zienkiewicz

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