MEDITERRANEAN DIET AND CANCER PREVENTION

Authors

DOI:

https://doi.org/10.31435/ijitss.2(50).2026.5511

Keywords:

Mediterranean Diet, Vitamin C, Vitamin E, Omega-3 Fatty Acids, Dietary Fibre, Cancer Prevention, Cancer Statistic

Abstract

The Mediterranean diet (MedDiet) is one of the most frequently recommended dietary models for the prevention of lifestyle diseases, including cancers. Unlike restrictive diets, it does not require significant dietary restrictions, is safe and does not lead to deficiencies. It is characterized by a high content of vitamins, fiber and anti-inflammatory and antioxidant substances.

Aim and methods: The aim of this study is to analyze the effect of the Mediterranean diet on cancer prevention. Information was collected from scientific publications available in PubMed, Scopus and Google Scholar databases.

Results: Previous research indicates that MedDiet benefits cardiovascular health, reduces the risk of metabolic syndrome and neurodegenerative diseases. A growing body of evidence also points to its role in the prevention of cancers such as breast, lung, liver and colorectal cancers. A high intake of vegetables, fruits, fish, olive oil and nuts is associated with a lower risk of developing these diseases.

References

Serra-Majem, L., Román-Viñas, B., Sanchez-Villegas, A., Guasch-Ferré, M., Corella, D., & La Vecchia, C. (2019). Benefits of the Mediterranean diet: Epidemiological and molecular aspects. Molecular Aspects of Medicine, 67, 1–55. https://doi.org/10.1016/j.mam.2019.06.001

Bucciantini, M., Leri, M., Nardiello, P., Casamenti, F., & Stefani, M. (2021). Olive polyphenols: Antioxidant and anti-inflammatory properties. Antioxidants, 10(7), 1044. https://doi.org/10.3390/antiox10071044

American Heart Association. (n.d.). What is the Mediterranean diet? https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/mediterranean-diet

Kiani, A. K., Medori, M. C., Bonetti, G., Aquilanti, B., Velluti, V., Matera, G., Iaconelli, A., Stuppia, L., Connelly, S. T., Herbst, K. L., & Bertelli, M. (2022). Modern vision of the Mediterranean diet. Journal of Preventive Medicine and Hygiene, 63(2 Suppl. 3), E36–E43. https://doi.org/10.15167/2421-4248/jpmh2022.63.2S3.2745

Liu, X., Morris, M. C., Dhana, K., Ventrelle, J., Johnson, K., Bishop, L., Hollings, C. S., Boulin, A., Laranjo, N., Stubbs, B. J., Reilly, X., Carey, V. J., Wang, Y., Furtado, J. D., Marcovina, S. M., Tangney, C., Aggarwal, N. T., Arfanakis, K., Sacks, F. M., & Barnes, L. L. (2021). Mediterranean-DASH intervention for neurodegenerative delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline. Contemporary Clinical Trials, 102, 106270. https://doi.org/10.1016/j.cct.2021.106270

Guasch-Ferré, M., & Willett, W. C. (2021). The Mediterranean diet and health: A comprehensive overview. Journal of Internal Medicine, 290(3), 549–566. https://doi.org/10.1111/joim.13333

Konieczna, J., Ruiz-Canela, M., Galmes-Panades, A. M., Abete, I., Babio, N., Fiol, M., Martín-Sánchez, V., Estruch, R., Vidal, J., Buil-Cosiales, P., García-Gavilán, J. F., Moñino, M., Marcos-Delgado, A., Casas, R., Olbeyra, R., Fitó, M., Hu, F. B., Martínez-Gonzalez, M. Á., Martínez, J. A., ... Salas-Salvadó, J. (2023). An energy-reduced Mediterranean diet, physical activity, and body composition: An interim subgroup analysis of the PREDIMED-Plus randomized clinical trial. JAMA Network Open, 6(10), e2337994. https://doi.org/10.1001/jamanetworkopen.2023.37994

Framingham Heart Study. (n.d.). Framingham Heart Study. https://www.framinghamheartstudy.org/

International Agency for Research on Cancer. (2022). Global Cancer Observatory 2022: All cancers fact sheet. World Health Organization. https://gco.iarc.who.int/media/globocan/factsheets/cancers/39-all-cancers-fact-sheet.pdf

International Agency for Research on Cancer. (n.d.). Estimated number of new cases from 2022 to 2050, both sexes, age [0–85+]. World Health Organization. https://gco.iarc.fr/tomorrow/en/dataviz/isotype?years=2050&types=0&single_unit=500000

Ubago-Guisado, E., Rodríguez-Barranco, M., Ching-López, A., Petrova, D., Molina-Montes, E., Amiano, P., Barricarte-Gurrea, A., Chirlaque, M. D., Agudo, A., & Sánchez, M. J. (2021). Evidence update on the relationship between diet and the most common cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) study: A systematic review. Nutrients, 13(10), 3582. https://doi.org/10.3390/nu13103582

Rock, C. L., Thomson, C., Gansler, T., Gapstur, S. M., McCullough, M. L., Patel, A. V., Andrews, K. S., Bandera, E. V., Spees, C. K., Robien, K., Hartman, S., Sullivan, K., Grant, B. L., Hamilton, K. K., Kushi, L. H., Caan, B. J., Kibbe, D., Black, J. D., Wiedt, T. L., ... Doyle, C. (2020). American Cancer Society guideline for diet and physical activity for cancer prevention. CA: A Cancer Journal for Clinicians, 70(4), 245–271. https://doi.org/10.3322/caac.21591

Abdeen, S. K., Mastandrea, I., Stinchcombe, N., Puschhof, J., & Elinav, E. (2025). Diet-microbiome interactions in cancer. Cancer Cell, 43(4), 680–707. https://doi.org/10.1016/j.ccell.2025.03.013

Locasale, J. W., Goncalves, M. D., Di Tano, M., & Burgos-Barragan, G. (2024). Diet and cancer metabolism. Cold Spring Harbor Perspectives in Medicine, 14(12), a041549. https://doi.org/10.1101/cshperspect.a041549

International Agency for Research on Cancer. (n.d.). Europejski kodeks walki z rakiem. World Health Organization. https://cancer-code-europe.iarc.fr/index.php/pl/

Mentella, M. C., Scaldaferri, F., Ricci, C., Gasbarrini, A., & Miggiano, G. A. D. (2019). Cancer and Mediterranean diet: A review. Nutrients, 11(9), 2059. https://doi.org/10.3390/nu11092059

Reytor-González, C., Zambrano, A. K., Montalvan, M., Frias-Toral, E., Simancas-Racines, A., & Simancas-Racines, D. (2024). Adherence to the Mediterranean diet and its association with gastric cancer: Health benefits from a Planeterranean perspective. Journal of Translational Medicine, 22, 483. https://doi.org/10.1186/s12967-024-05176-w

Torres, Á., Quintanilla, F., Barnafi, E., Sánchez, C., Acevedo, F., Walbaum, B., & Merino, T. (2024). Dietary interventions for cancer prevention: An update to ACS international guidelines. Nutrients, 16(17), 2897. https://doi.org/10.3390/nu16172897

Wei, X., Zhu, C., Ji, M., Fan, J., Xie, J., Huang, Y., Jiang, X., Xu, J., Yin, R., Du, L., Wang, Y., Dai, J., Jin, G., Xu, L., Hu, Z., Shen, H., Zhu, M., & Ma, H. (2021). Diet and risk of incident lung cancer: A large prospective cohort study in UK Biobank. The American Journal of Clinical Nutrition, 114(6), 2043–2051. https://doi.org/10.1093/ajcn/nqab298

El Kinany, K., Hatime, Z., El Asri, A., Benslimane, A., Mint Sidi Deoula, M., Zarrouq, B., Lagiou, P., & El Rhazi, K. (2025). Adherence to the Mediterranean diet and colorectal cancer risk: A large case control study in the Moroccan population. Public Health Nutrition, 28(1), e48. https://doi.org/10.1017/S1368980025000199

Chu, A. H., Lin, K., Croker, H., Kefyalew, S., Becerra-Tomás, N., Dossus, L., González-Gil, E. M., Ahmadi, N., Park, Y., Krebs, J., Weijenberg, M. P., Baskin, M. L., Copson, E., Lewis, S. J., Seidell, J. C., Chowdhury, R., Hill, L., Chan, D. S., Lee, D. H., & Giovannucci, E. L. (2025). Dietary patterns and colorectal cancer risk: Global Cancer Update Programme (CUP Global) systematic literature review. The American Journal of Clinical Nutrition, 121(5), 999–1016. https://doi.org/10.1016/j.ajcnut.2025.02.021

Quartiroli, M., Roncallo, C., Pala, V., Simeon, V., Ricceri, F., Venturelli, E., Pattaroni, L., Sieri, S., & Agnoli, C. (2024). Adherence to diet quality indices and breast cancer risk in the Italian ORDET cohort. Nutrients, 16(8), 1187. https://doi.org/10.3390/nu16081187

Downloads

Published

2026-06-29

How to Cite

Sidor, D., Kuźmiuk, D., Szostak, P., Maj, S., Procajło, K., Sikorski, A., Sikorska, W., Rynkowska, M., & Danio, J. (2026). MEDITERRANEAN DIET AND CANCER PREVENTION. International Journal of Innovative Technologies in Social Science, 4(2(50). https://doi.org/10.31435/ijitss.2(50).2026.5511